Q571K9 · Q571K9_MOUSE

  • Protein
    Phosphoinositide phospholipase C
  • Gene
    Plcb3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site367
Binding site368Ca2+ (UniProtKB | ChEBI)
Binding site397Ca2+ (UniProtKB | ChEBI)
Binding site399Ca2+ (UniProtKB | ChEBI)
Active site414
Binding site448Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functioncalcium ion binding
Molecular Functionphosphatidylinositol phospholipase C activity
Biological Processintracellular signal transduction
Biological Processlipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoinositide phospholipase C
  • EC number

Gene names

    • Name
      Plcb3
    • Synonyms
      mKIAA4098

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q571K9

Organism-specific databases

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-30Disordered
Region501-623Disordered
Compositional bias519-554Polar residues
Domain626-742PI-PLC Y-box
Domain743-871C2
Compositional bias923-938Polar residues
Region923-973Disordered
Compositional bias939-955Pro residues
Compositional bias956-973Polar residues

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    1,048
  • Mass (Da)
    117,162
  • Last updated
    2005-05-10 v1
  • Checksum
    E7B8433C7C3AA3FE
RRGARAGRAGACGESSGTVGSRRGSVGPRAAPGLAMAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALESCGLNFNRSESIRPDEFPLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYLGGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIDPLDKYPLSAGIPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEESLSREPNVPMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDKKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQETPCQQPGSQLPSNPTPNPLDASPRWPPGPTTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSPSAL

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias519-554Polar residues
Compositional bias923-938Polar residues
Compositional bias939-955Pro residues
Compositional bias956-973Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK220180
EMBL· GenBank· DDBJ
BAD90365.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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