Q566S4 · Q566S4_DANRE

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
  • Alternative names
    • Complex I-30kD
    • NADH-ubiquinone oxidoreductase 30 kDa subunit

Gene names

    • Name
      ndufs3
    • Synonyms
      zgc:112520

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q566S4

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Subunit

Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with NDUFAF3. Interacts with RAB5IF. Found in subcomplexes containing subunits NDUFS2, MT-ND1 and NDUFA13.

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain79-200NADH:ubiquinone oxidoreductase 30kDa subunit
Region235-255Disordered

Sequence similarities

Belongs to the complex I 30 kDa subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    29,398
  • Last updated
    2005-05-10 v1
  • Checksum
    C6CC9D5CC56B76A1
MAASLVRFVRSGFGRSLNVARQSAAIVQTRSTTTESRPTVRPKDPVTHSQLSEFGEYVAEILPKYVQQVQVTCFNELEIMVHPEGIIPVLTFLKDHTNAQFRNLADLTAVDIPSKQNRFEIVYNLLSLHYNSRIRVKTYTDELTPLDSSVPVFQASNWYEREVWDMFGVFFTNHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPAYRGPKDAPKLESGDKSEK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC093359
EMBL· GenBank· DDBJ
AAH93359.1
EMBL· GenBank· DDBJ
mRNA
BC165450
EMBL· GenBank· DDBJ
AAI65450.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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