Q55FQ9 · LMPC_DICDI

Function

function

May act as a lysosomal receptor (By similarity).
May be involved role in macropinocytosis and fluid phase exocytosis

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentlysosomal membrane
Cellular Componentlysosome
Cellular Componentphagocytic vesicle
Cellular Componentphagolysosome
Cellular Componentvesicle membrane
Molecular Functionscavenger receptor activity
Biological Processphagocytosis, engulfment

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysosome membrane protein 2-C
  • Alternative names
    • Lysosome membrane protein II-3 (LIMP II-3)

Gene names

    • Name
      lmpC
    • ORF names
      DDB_G0267440

Organism names

Accessions

  • Primary accession
    Q55FQ9
  • Secondary accessions
    • Q9BKJ8

Proteomes

Organism-specific databases

Subcellular Location

Lysosome membrane
; Multi-pass membrane protein
Note: Localizes to membranes of endolysosomal vesicles and macropinosomes.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-7Cytoplasmic
Transmembrane8-28Helical
Topological domain29-739Lumenal
Transmembrane740-760Helical
Topological domain761-782Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00003277591-782Lysosome membrane protein 2-C
Glycosylation77N-linked (GlcNAc...) asparagine
Glycosylation105N-linked (GlcNAc...) asparagine
Glycosylation191N-linked (GlcNAc...) asparagine
Glycosylation219N-linked (GlcNAc...) asparagine
Glycosylation234N-linked (GlcNAc...) asparagine
Glycosylation243N-linked (GlcNAc...) asparagine
Glycosylation281N-linked (GlcNAc...) asparagine
Glycosylation368N-linked (GlcNAc...) asparagine
Glycosylation387N-linked (GlcNAc...) asparagine
Glycosylation401N-linked (GlcNAc...) asparagine
Glycosylation427N-linked (GlcNAc...) asparagine
Glycosylation432N-linked (GlcNAc...) asparagine
Glycosylation451N-linked (GlcNAc...) asparagine
Glycosylation465N-linked (GlcNAc...) asparagine
Glycosylation501N-linked (GlcNAc...) asparagine
Glycosylation536N-linked (GlcNAc...) asparagine
Glycosylation540N-linked (GlcNAc...) asparagine
Glycosylation595N-linked (GlcNAc...) asparagine
Glycosylation605N-linked (GlcNAc...) asparagine
Glycosylation613N-linked (GlcNAc...) asparagine
Glycosylation646N-linked (GlcNAc...) asparagine
Glycosylation692N-linked (GlcNAc...) asparagine

Post-translational modification

Heavily glycosylated.

Keywords

Proteomic databases

PTM databases

Expression

Developmental stage

Found at all stages of development in comparable quantities (at protein level).

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif777-781Tyrosine-type lysosomal sorting signal

Sequence similarities

Belongs to the CD36 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    782
  • Mass (Da)
    87,876
  • Last updated
    2005-05-24 v1
  • Checksum
    5FA958647B487976
MVANNKGLLIAGLLLSVIGAALFVISLALLPSVLNVATNNAIVDAVIVDSFKSQRYNDWAGQKSVDNYFKQYYYLWNLTNPNEVLNGKNCNFEKIGPFNYKYEWNNSKVSFSDDGNLINYIQSKSYKWIEGEDSLNPFTVSTTNFNPAYLGLLSTLSKNSITLGMTAEDLLYTLASAPQTKQFLEYLSSDNFTMIAYFYNGPKYFNQQYQLLLSTINNNLTTTPTIYFLEQWSNSTIIPTNGNSSLWDNMLISYGLDSPSGISLQSALEILNPMNQYSLLNSTNGISYWINAVFNGPNSNSYQILEQELGINQAQLTLVMIWWLKGFNDQYTMSQLLKQCEIESIELLGVCQFITTIPLGYKSISQFNITNLPWLEPIEIPIAMGTNLTISTNEAQSNLFNDSIDDSLLTIHGLGLFLEQMSTNSNNFTKWNLTNNDAMTMIGYFLSYIPNTTGYSIKSVQSFYNTSGLIVTRTANEWLWDCQDDLLDYLGIDQQCSFQQNNTIFKPSTVYTGKKDLSLTNQYQQFQEQSTLTIWNGTVNVTGFVENGQMAPLVQDNLPQSLTIFEENILRPLSLVHSSSSSVMGVSTQRYYLPNQSFPIDPVFNNSINGFANLTGLFNGVPIYVSLWDMYGVPIEYSSLYINGLNQTYENAEIPLDLEPITGNTLYYNLKLQINLQIPSNANSLWFSSLGNWTNIFSPTNSNSFGIFYPSLKIGQTATASTNDINLLKQQFKQIQTVKIAPVVVVSIFGGILLIAGLVMAINGFRKTFYNNNQYNGYNIIN

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict5in Ref. 1; AAK30041

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF238325
EMBL· GenBank· DDBJ
AAK30041.1
EMBL· GenBank· DDBJ
mRNA
AAFI02000003
EMBL· GenBank· DDBJ
EAL73172.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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