Q550Q4 · RHEB_DICDI

Function

function

Binds GTP and exhibits intrinsic GTPase activity.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site18GTP (UniProtKB | ChEBI)
Binding site19GTP (UniProtKB | ChEBI)
Binding site20GTP (UniProtKB | ChEBI)
Binding site20Mg2+ (UniProtKB | ChEBI)
Binding site21GTP (UniProtKB | ChEBI)
Binding site35GTP (UniProtKB | ChEBI)
Binding site38GTP (UniProtKB | ChEBI)
Binding site38Mg2+ (UniProtKB | ChEBI)
Binding site119GTP (UniProtKB | ChEBI)
Binding site122GTP (UniProtKB | ChEBI)
Binding site150GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentautophagosome
Cellular Componentcytoplasmic vesicle
Cellular Componentplasma membrane
Molecular FunctionGDP binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmetal ion binding
Biological Processnegative regulation of phagocytosis
Biological Processpositive regulation of TOR signaling
Biological Processsmall GTPase-mediated signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GTP-binding protein Rheb homolog
  • EC number

Gene names

    • Name
      rheb
    • ORF names
      DDB_G0277041

Organism names

Accessions

  • Primary accession
    Q550Q4
  • Secondary accessions
    • Q7KWW6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue, lipidation, propeptide.

TypeIDPosition(s)Description
ChainPRO_00003276981-182GTP-binding protein Rheb homolog
Modified residue182Cysteine methyl ester
Lipidation182S-farnesyl cysteine
PropeptidePRO_0000327699183-185Removed in mature form

Keywords

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif35-43Effector region

Sequence similarities

Belongs to the small GTPase superfamily. Rheb family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    185
  • Mass (Da)
    20,715
  • Last updated
    2005-05-24 v1
  • Checksum
    586ADA3B17BCC990
MAPQKHRKICVMGSRAVGKSTITMQFVESHCPDSYHPTIENTYQKIIRHQGQEYSVEIIDTAGQDEYSILQKQYSIGIHGYILVYSVTSVSSLEVIKVLNDKILSSLGAEKIPRVLVGNKSDLDNERNISRDQGIQLANEWECAFVECSGKNNENVEEVFKQILNEVNKGSTGPEPPQKEGCILM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAFI02000019
EMBL· GenBank· DDBJ
EAL69022.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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