Q54YZ0 · UGPA2_DICDI
- ProteinUTP--glucose-1-phosphate uridylyltransferase 2
- GeneugpB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids502 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Plays a central role as a glucosyl donor in cellular metabolic pathways.
Catalytic activity
- alpha-D-glucose 1-phosphate + UTP + H+ = UDP-alpha-D-glucose + diphosphate
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 114-117 | UTP (UniProtKB | ChEBI) | |||
Binding site | 116-117 | substrate | |||
Binding site | 128 | UTP (UniProtKB | ChEBI) | |||
Binding site | 191 | UTP (UniProtKB | ChEBI) | |||
Binding site | 220 | UTP (UniProtKB | ChEBI) | |||
Binding site | 221 | substrate | |||
Binding site | 249-251 | substrate | |||
Binding site | 251 | UTP (UniProtKB | ChEBI) | |||
Binding site | 390 | UTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | extracellular matrix | |
Molecular Function | UTP:glucose-1-phosphate uridylyltransferase activity | |
Biological Process | autophagosome assembly | |
Biological Process | cellulose biosynthetic process | |
Biological Process | culmination involved in sorocarp development | |
Biological Process | glycogen metabolic process | |
Biological Process | UDP-glucose metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUTP--glucose-1-phosphate uridylyltransferase 2
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionQ54YZ0
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Phenotypes & Variants
Disruption phenotype
Cells undergo aberrant differentiation and development ending with small, gnarled fruiting bodies. They also have decreased spore viability and decreased levels of glycogen.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000327942 | 1-502 | UTP--glucose-1-phosphate uridylyltransferase 2 | ||
Proteomic databases
Expression
Developmental stage
Expressed in both prestalk and prespore cells. Expression becomes strong after 12 hours of development and peaks at 16 hours.
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length502
- Mass (Da)56,268
- Last updated2005-05-24 v1
- MD5 Checksum6339E032651CE379FEF27FC87BEEE276
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 18 | in Ref. 1; AAD34028 | |||
Sequence conflict | 320 | in Ref. 3; AAA91057 | |||
Sequence conflict | 363-364 | in Ref. 3; AAA91057 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF150929 EMBL· GenBank· DDBJ | AAD34028.1 EMBL· GenBank· DDBJ | mRNA | ||
AAFI02000023 EMBL· GenBank· DDBJ | EAL68112.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
L28007 EMBL· GenBank· DDBJ | AAA91057.1 EMBL· GenBank· DDBJ | Genomic DNA |