Q54YZ0 · UGPA2_DICDI

Function

function

Plays a central role as a glucosyl donor in cellular metabolic pathways.

Catalytic activity

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site114-117UTP (UniProtKB | ChEBI)
Binding site116-117substrate
Binding site128UTP (UniProtKB | ChEBI)
Binding site191UTP (UniProtKB | ChEBI)
Binding site220UTP (UniProtKB | ChEBI)
Binding site221substrate
Binding site249-251substrate
Binding site251UTP (UniProtKB | ChEBI)
Binding site390UTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentextracellular matrix
Molecular FunctionUTP:glucose-1-phosphate uridylyltransferase activity
Biological Processautophagosome assembly
Biological Processcellulose biosynthetic process
Biological Processculmination involved in sorocarp development
Biological Processglycogen metabolic process
Biological ProcessUDP-glucose metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UTP--glucose-1-phosphate uridylyltransferase 2
  • EC number
  • Alternative names
    • UDP-glucose pyrophosphorylase 2 (UDPGP 2; UGPase 2)

Gene names

    • Name
      ugpB
    • ORF names
      DDB_G0277879

Organism names

Accessions

  • Primary accession
    Q54YZ0
  • Secondary accessions
    • Q27566
    • Q9XZN2

Proteomes

Organism-specific databases

Subcellular Location

Phenotypes & Variants

Disruption phenotype

Cells undergo aberrant differentiation and development ending with small, gnarled fruiting bodies. They also have decreased spore viability and decreased levels of glycogen.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003279421-502UTP--glucose-1-phosphate uridylyltransferase 2

Proteomic databases

Expression

Developmental stage

Expressed in both prestalk and prespore cells. Expression becomes strong after 12 hours of development and peaks at 16 hours.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-20Disordered

Sequence similarities

Belongs to the UDPGP type 1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    502
  • Mass (Da)
    56,268
  • Last updated
    2005-05-24 v1
  • MD5 Checksum
    6339E032651CE379FEF27FC87BEEE276
MMKPDLNSPLPQSPQLQAFGSRSSDLATEDLFLKKLEAISQTAPNETVKNEFLNKEIPSINKLFTRFLKNRKKVIDWDKINPPPADMVLNYKDLPAITEQRTSELASKLAVLKLNGGLGTTMGCTGPKSVIEVRSEKTFLDLSVQQIKEMNERYNIKVPLVLMNSFNTHQETGKIIQKYKYSDVKIHSFNQSRFPRILKDNLMPVPDKLFGSDSEWYPPGHGDVFFALQNSGLLETLINEGKEYLFISNVDNLGAVVDFNILEAMDKNKVEYIMEVTNKTRADVKGGTLIQYEGKAKLLEIAQVPSSKVEEFKSIKKFKIFNTNNIWVNLKAMDRILKQNLLDDMDIIINPKVADGKNIIQLEIAAGAAIEFFNNARGVNVPRSRFLPVKSTSDLFIVQSNLYSLEKGVLVMNKNRPFTTVPLVKLGDNFKKVSDYQARIKGIPDILELDQLTVSGDITFGPNMVLKGTVIIVANHGSRIDIPEGSEFENKVVSGNLHCGAL

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict18in Ref. 1; AAD34028
Sequence conflict320in Ref. 3; AAA91057
Sequence conflict363-364in Ref. 3; AAA91057

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF150929
EMBL· GenBank· DDBJ
AAD34028.1
EMBL· GenBank· DDBJ
mRNA
AAFI02000023
EMBL· GenBank· DDBJ
EAL68112.1
EMBL· GenBank· DDBJ
Genomic DNA
L28007
EMBL· GenBank· DDBJ
AAA91057.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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