Q54WH5 · ELMOE_DICDI
- ProteinELMO domain-containing protein E
- GeneelmoE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1677 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell leading edge | |
Cellular Component | cytoplasm | |
Cellular Component | macropinosome | |
Molecular Function | G-protein beta-subunit binding | |
Molecular Function | small GTPase binding | |
Biological Process | actin filament organization | |
Biological Process | actin filament polymerization | |
Biological Process | cell motility | |
Biological Process | chemotaxis to cAMP | |
Biological Process | response to differentiation-inducing factor 1 |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameELMO domain-containing protein E
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionQ54WH5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000333282 | 1-1677 | ELMO domain-containing protein E | |||
Sequence: MKLQIYNPNGEEFQYDFKSDIPFSFHIKNLYENLVVHNNGLKKILQSFPYCEANRSYDEIYSHYSLQEATSGNWMSNSTDSTFIKGSPDNTLFFKLKPLTHYLTPIEKLIGTTTSSSSSSSSPSSSSSSSSSSSSSSPSSPSLIGLILSLQTHLALLMYENIYGNKNNSKDTNNSGTINNNNNNNNNSGGSNIKLSSTPSSSFLTFPTSTSNLLLSSDVIKKILNIVFLAPSPQSLQLLVFLVSNSPSNDDLLSQISNTHSNSQLHGFSIGGGGGGSGNNSSITSIGGGDSKKIENKDNSGSAVVGSQSNSPQSSSFVKSQQIQQQQQYQKPNNSSPPPTTTTTTTTTTTTSGSQVKLSVGGNSGSFNNTTESSPSLFTLVDTAIKSVSTEHSSNFYLHILNNPAYNEVIETHFEMVCLILSLINNMYRLSPNPINYFNRLHNDSILKYIMEFAKKNQKIYQNTQYIVLRNYLMKELHMQRLHPINVDKVLSHQILLSDLWGSALSSYPFGGINSEHWLLLGFRSSNPMEDFKNTGVLALRNLSYFSKQHLQPFQSLLLTQTKREKDDNDNNNNKVIDKPIITNKFNIETLDDDNDNNNNQELNNNNNNNNNNNYNIKTKPRSNSRSYPLATVAISLTYTLSNIFRIGRINDSPIDSSIWDIAFSGSNWFDEIFVTTFNLFESLWHSEAHSYSDFPQVISHTREIIEKVCSKSPINLQDFKDKLTTLLEKKDEISSLDVNTVETLARYHQLQPSHINKRHIHKFFGERVNVDKLPNSNNPTDNIITTNTNTTTTTTTSTNNDCESTILQDHIESDKNNDDNNNNNEIIDDCESNSSFLVSSNTKEFSGKNLIKFFGEKTDQKEQYSTQPSNVKSYKLKNFFGDQPVVINKNGGGGGGGGGGGVDNELNQGGETVNKNKNDLIDDSDDENDNDEVNNNNNSNRINQDINHKLYGNSPISERNHRLHVFFGEWFDTEQVEYNEKIRSSSSTPDTSSPPLNSQPESARLHKLNKFFGERVNIPISKPKVIGEGGGGGIFPIDDIDVTDGSTNNHHIGGGGGGGSSDNLLSRSPEETRSDFKAQKVLGERLDIKKEKESINFASQPSNVREYKLHKLFGEMVPAHKQKSPKLQGGSGPWKKGNVSKSDSQAVVAPLNTIKFNNGNTNMNPLLQSCPTPINSPTSLSSDHLLDDVLDLNQTNNNIDNENDDINEAIIPPSLSPTLLGVNNHGEEEEEEEEEEEGYNHTQDNHAQDNHAQDNLLLLDDDDDTKSEPIPSTNTLLDSDIIPNNTTTTTTTTTTTTTTTTNTTGQKRISILSTDTNRPGSSNYGESSLSNGSRFDGIPESTTHNANGDDDHQINLHSSSPQPLPKFVNTDDEDNNNNNNNKKQDDDEDDEDDDDKEEIRKKRENKTNHRLHVFFGERFDVENIHFFTRVSSSPGSYDAHLNNPHLSVSPQPETVRSYKLKKFFGKNPEDNVTLSSSYDSSTSPLLSQLNHHHHHNHHQSASNLINNINNNNNNNNNNNSNNNSNNQNNLNSSNNSNNSSISNNSGKNNTNNNNNNNTNNNNDNSPSTSPSSSFKKHQYQYVSAEDPEGDVSKTNEIRKLRRDFKTQRILGERLNIKKESTVVAFQDQPSTIKVDKLISLFGEKVGFSLKRKESQRDLQHQASSSNLKFSLASSSK |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 112-139 | Disordered | ||||
Sequence: TTTSSSSSSSSPSSSSSSSSSSSSSSPS | ||||||
Region | 168-194 | Disordered | ||||
Sequence: NSKDTNNSGTINNNNNNNNNSGGSNIK | ||||||
Compositional bias | 264-289 | Polar residues | ||||
Sequence: QLHGFSIGGGGGGSGNNSSITSIGGG | ||||||
Region | 264-372 | Disordered | ||||
Sequence: QLHGFSIGGGGGGSGNNSSITSIGGGDSKKIENKDNSGSAVVGSQSNSPQSSSFVKSQQIQQQQQYQKPNNSSPPPTTTTTTTTTTTTSGSQVKLSVGGNSGSFNNTTE | ||||||
Compositional bias | 298-372 | Polar residues | ||||
Sequence: DNSGSAVVGSQSNSPQSSSFVKSQQIQQQQQYQKPNNSSPPPTTTTTTTTTTTTSGSQVKLSVGGNSGSFNNTTE | ||||||
Domain | 492-710 | ELMO | ||||
Sequence: SHQILLSDLWGSALSSYPFGGINSEHWLLLGFRSSNPMEDFKNTGVLALRNLSYFSKQHLQPFQSLLLTQTKREKDDNDNNNNKVIDKPIITNKFNIETLDDDNDNNNNQELNNNNNNNNNNNYNIKTKPRSNSRSYPLATVAISLTYTLSNIFRIGRINDSPIDSSIWDIAFSGSNWFDEIFVTTFNLFESLWHSEAHSYSDFPQVISHTREIIEKVC | ||||||
Region | 592-625 | Disordered | ||||
Sequence: DDDNDNNNNQELNNNNNNNNNNNYNIKTKPRSNS | ||||||
Compositional bias | 593-625 | Polar residues | ||||
Sequence: DDNDNNNNQELNNNNNNNNNNNYNIKTKPRSNS | ||||||
Region | 775-801 | Disordered | ||||
Sequence: PNSNNPTDNIITTNTNTTTTTTTSTNN | ||||||
Region | 888-947 | Disordered | ||||
Sequence: INKNGGGGGGGGGGGVDNELNQGGETVNKNKNDLIDDSDDENDNDEVNNNNNSNRINQDI | ||||||
Region | 982-1002 | Disordered | ||||
Sequence: KIRSSSSTPDTSSPPLNSQPE | ||||||
Region | 1047-1075 | Disordered | ||||
Sequence: STNNHHIGGGGGGGSSDNLLSRSPEETRS | ||||||
Region | 1122-1141 | Disordered | ||||
Sequence: KQKSPKLQGGSGPWKKGNVS | ||||||
Coiled coil | 1186-1212 | |||||
Sequence: LLDDVLDLNQTNNNIDNENDDINEAII | ||||||
Region | 1197-1248 | Disordered | ||||
Sequence: NNNIDNENDDINEAIIPPSLSPTLLGVNNHGEEEEEEEEEEEGYNHTQDNHA | ||||||
Region | 1261-1404 | Disordered | ||||
Sequence: DDDDDTKSEPIPSTNTLLDSDIIPNNTTTTTTTTTTTTTTTTNTTGQKRISILSTDTNRPGSSNYGESSLSNGSRFDGIPESTTHNANGDDDHQINLHSSSPQPLPKFVNTDDEDNNNNNNNKKQDDDEDDEDDDDKEEIRKKR | ||||||
Compositional bias | 1270-1345 | Polar residues | ||||
Sequence: PIPSTNTLLDSDIIPNNTTTTTTTTTTTTTTTTNTTGQKRISILSTDTNRPGSSNYGESSLSNGSRFDGIPESTTH | ||||||
Compositional bias | 1353-1376 | Polar residues | ||||
Sequence: HQINLHSSSPQPLPKFVNTDDEDN | ||||||
Region | 1434-1454 | Disordered | ||||
Sequence: SPGSYDAHLNNPHLSVSPQPE | ||||||
Region | 1467-1593 | Disordered | ||||
Sequence: KNPEDNVTLSSSYDSSTSPLLSQLNHHHHHNHHQSASNLINNINNNNNNNNNNNSNNNSNNQNNLNSSNNSNNSSISNNSGKNNTNNNNNNNTNNNNDNSPSTSPSSSFKKHQYQYVSAEDPEGDVS | ||||||
Compositional bias | 1470-1490 | Polar residues | ||||
Sequence: EDNVTLSSSYDSSTSPLLSQL | ||||||
Compositional bias | 1501-1580 | Polar residues | ||||
Sequence: SASNLINNINNNNNNNNNNNSNNNSNNQNNLNSSNNSNNSSISNNSGKNNTNNNNNNNTNNNNDNSPSTSPSSSFKKHQY | ||||||
Region | 1654-1677 | Disordered | ||||
Sequence: ESQRDLQHQASSSNLKFSLASSSK | ||||||
Compositional bias | 1660-1677 | Polar residues | ||||
Sequence: QHQASSSNLKFSLASSSK |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,677
- Mass (Da)186,261
- Last updated2005-05-24 v1
- Checksum36DA15F289BCAA3E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 264-289 | Polar residues | ||||
Sequence: QLHGFSIGGGGGGSGNNSSITSIGGG | ||||||
Compositional bias | 298-372 | Polar residues | ||||
Sequence: DNSGSAVVGSQSNSPQSSSFVKSQQIQQQQQYQKPNNSSPPPTTTTTTTTTTTTSGSQVKLSVGGNSGSFNNTTE | ||||||
Compositional bias | 593-625 | Polar residues | ||||
Sequence: DDNDNNNNQELNNNNNNNNNNNYNIKTKPRSNS | ||||||
Compositional bias | 1270-1345 | Polar residues | ||||
Sequence: PIPSTNTLLDSDIIPNNTTTTTTTTTTTTTTTTNTTGQKRISILSTDTNRPGSSNYGESSLSNGSRFDGIPESTTH | ||||||
Compositional bias | 1353-1376 | Polar residues | ||||
Sequence: HQINLHSSSPQPLPKFVNTDDEDN | ||||||
Compositional bias | 1470-1490 | Polar residues | ||||
Sequence: EDNVTLSSSYDSSTSPLLSQL | ||||||
Compositional bias | 1501-1580 | Polar residues | ||||
Sequence: SASNLINNINNNNNNNNNNNSNNNSNNQNNLNSSNNSNNSSISNNSGKNNTNNNNNNNTNNNNDNSPSTSPSSSFKKHQY | ||||||
Compositional bias | 1660-1677 | Polar residues | ||||
Sequence: QHQASSSNLKFSLASSSK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAFI02000032 EMBL· GenBank· DDBJ | EAL67603.1 EMBL· GenBank· DDBJ | Genomic DNA |