Q54P13 · ABCC8_DICDI
- ProteinABC transporter C family member 8
- GeneabcC8
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1593 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled transmembrane transporter activity | |
Biological Process | culmination involved in sorocarp development | |
Biological Process | sorocarp morphogenesis | |
Biological Process | transmembrane transport |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameABC transporter C family member 8
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionQ54P13
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 27-47 | Helical | ||||
Sequence: VVMTLPAIYLLIFGMKRLYYL | ||||||
Transmembrane | 75-95 | Helical | ||||
Sequence: VIVSILLVAWKILFFIVIVSI | ||||||
Transmembrane | 100-120 | Helical | ||||
Sequence: FEILYSVVTVVQWTVSLGLVY | ||||||
Transmembrane | 135-155 | Helical | ||||
Sequence: LYWVFAFFVATVKLRTLTLAI | ||||||
Transmembrane | 169-189 | Helical | ||||
Sequence: FSYFVGYCLILILSITSVLFF | ||||||
Transmembrane | 280-300 | Helical | ||||
Sequence: FYIAALFKIIQDLLIFVGPTL | ||||||
Transmembrane | 318-338 | Helical | ||||
Sequence: YDGLIYALLYFLAPVVQSLLL | ||||||
Transmembrane | 392-412 | Helical | ||||
Sequence: LCPYLHMIWSAPLQLAISLVL | ||||||
Transmembrane | 419-439 | Helical | ||||
Sequence: ASVFAGLGIMLVMIPINLAIS | ||||||
Transmembrane | 505-525 | Helical | ||||
Sequence: LLLWSMSPVFVSVSTFTVYIL | ||||||
Transmembrane | 1005-1025 | Helical | ||||
Sequence: IGVLLATCIIGFYVLTQLLSI | ||||||
Transmembrane | 1064-1084 | Helical | ||||
Sequence: AKYYLSIYVAFSCGTIAATFL | ||||||
Transmembrane | 1157-1177 | Helical | ||||
Sequence: IIVIAWVSPFIILAMVPVGAL | ||||||
Transmembrane | 1251-1271 | Helical | ||||
Sequence: LAIRLEFLGACLVSCAVLYTV | ||||||
Transmembrane | 1280-1300 | Helical | ||||
Sequence: GTAGLVITYALAITGNMNWMV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000363853 | 1-1593 | ABC transporter C family member 8 | |||
Sequence: MGFCGDEPFTVWHNDSGDFSKCFEDSVVMTLPAIYLLIFGMKRLYYLENKKPDLFTLKQLSQDFQTWRKTLQLEVIVSILLVAWKILFFIVIVSIYNKPFEILYSVVTVVQWTVSLGLVYLEMKKGQSRSWEIRLYWVFAFFVATVKLRTLTLAIAGKSIYNVGFLEYFSYFVGYCLILILSITSVLFFDNLESYQNLEENEISKEVNANLFSRLTFWWINSVLVKGHKKALEISDVPTLGEIDQSILLSEKFEKAWEEQLKKPNPSLPWALAKAFGPHFYIAALFKIIQDLLIFVGPTLLKRVLGFVESRDGSQDTYDGLIYALLYFLAPVVQSLLLHQYFHRCYRVGMWLRSAVVTAVYKKALKTSLREGTTIGEIVNLMSVDAQKFMDLCPYLHMIWSAPLQLAISLVLLYRILNASVFAGLGIMLVMIPINLAISNLAKKRQTISMKLKDRRTKAVNEVLNGIKVIKLYSWEQSFMDHVNEIRNKELDVMKAIKYIQGFSLLLWSMSPVFVSVSTFTVYILTGQVLSATQAFPALSLFNVMQFPINMLPSVVSSIIEASVSVARLQKFLLKKDLDPNVVEHHINEPGIAVKIDNATLEWEPNKPILHDINLTIKKGELVAIVGQVGSGKSSIVSSLVGDLDKTKGTVAVNGSVALVSQQAWIQNATLKNNILFAKELNQDKYQSVVQACCLEPDIKILPGGDQTEIGEKGINLSGGQKQRVSIARAVYNNADIYIFDDPLSAVDAHVGKAIFKNVLSNQDGILCNKTRILVTHAVHYLPYVDRIILMKDGRIVEEGDFNTLIEAGSHFTELMSHDEQQQQLQQQQAPDKSSDSNEQIGGGDNKESENNEEQNEEEEGENENLLEKVLRKSRSRSPSPSSNRNIDGDDIASGSILQTTRTPEEDEQDERELMEDIDIDGGENIQTPLQKGEKSSVLKQPLRLLKKLPTSINKKLNNSGSGVSLKPITTVNAKPQDKNKIISVETKQEGKVSFKIYLSYFKAIGVLLATCIIGFYVLTQLLSILANWWISIWTNSYGGNGNGSGSGSISLSSSSTVEDNEKAKYYLSIYVAFSCGTIAATFLRSFSMVFGSIKGSKLFHEKMFKAVILSPMSFFDTTPIGRILNRFSKDQLTIDESIARTLGMFLNTFCQVVGSIIVIAWVSPFIILAMVPVGALFYFIQKYYLNSSRELTRLEGVSRSPIYAHFSETLAGVTTIRAFKDVARFVTENERLLDENQKCYYINISSNRWLAIRLEFLGACLVSCAVLYTVLARSRIEAGTAGLVITYALAITGNMNWMVRMSCDLENSVVSIERIQEYCLLPSEAPLFNDKSVPMSWPSHGKIVFKNLWLTYREGLDPVLRGINCTIEPKTKVGIVGRTGAGKSSLTQALFRLVEPLRGTIEIDGIDITELGLNPLRSRMAIIPQDPVLFAGSVRYNLDPFDQYDDHEIWEAIENAHLLKAIKDLDGGLDAMVQDGGDNFSVGQRQLLVIGRALLKKANIIVLDEASSSIDIASDALIQETIRTKFADCTVLTIAHRLGTIADSDKIMVLDKGELIEYDSPSELLKNQDSIYYSLVKASESKQNIDNDDESN |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 280-561 | ABC transmembrane type-1 1 | ||||
Sequence: FYIAALFKIIQDLLIFVGPTLLKRVLGFVESRDGSQDTYDGLIYALLYFLAPVVQSLLLHQYFHRCYRVGMWLRSAVVTAVYKKALKTSLREGTTIGEIVNLMSVDAQKFMDLCPYLHMIWSAPLQLAISLVLLYRILNASVFAGLGIMLVMIPINLAISNLAKKRQTISMKLKDRRTKAVNEVLNGIKVIKLYSWEQSFMDHVNEIRNKELDVMKAIKYIQGFSLLLWSMSPVFVSVSTFTVYILTGQVLSATQAFPALSLFNVMQFPINMLPSVVSSIIE | ||||||
Domain | 594-818 | ABC transporter 1 | ||||
Sequence: VKIDNATLEWEPNKPILHDINLTIKKGELVAIVGQVGSGKSSIVSSLVGDLDKTKGTVAVNGSVALVSQQAWIQNATLKNNILFAKELNQDKYQSVVQACCLEPDIKILPGGDQTEIGEKGINLSGGQKQRVSIARAVYNNADIYIFDDPLSAVDAHVGKAIFKNVLSNQDGILCNKTRILVTHAVHYLPYVDRIILMKDGRIVEEGDFNTLIEAGSHFTELMSH | ||||||
Compositional bias | 816-845 | Polar residues | ||||
Sequence: MSHDEQQQQLQQQQAPDKSSDSNEQIGGGD | ||||||
Region | 816-938 | Disordered | ||||
Sequence: MSHDEQQQQLQQQQAPDKSSDSNEQIGGGDNKESENNEEQNEEEEGENENLLEKVLRKSRSRSPSPSSNRNIDGDDIASGSILQTTRTPEEDEQDERELMEDIDIDGGENIQTPLQKGEKSSV | ||||||
Coiled coil | 844-875 | |||||
Sequence: GDNKESENNEEQNEEEEGENENLLEKVLRKSR | ||||||
Compositional bias | 876-902 | Polar residues | ||||
Sequence: SRSPSPSSNRNIDGDDIASGSILQTTR | ||||||
Domain | 1010-1308 | ABC transmembrane type-1 2 | ||||
Sequence: ATCIIGFYVLTQLLSILANWWISIWTNSYGGNGNGSGSGSISLSSSSTVEDNEKAKYYLSIYVAFSCGTIAATFLRSFSMVFGSIKGSKLFHEKMFKAVILSPMSFFDTTPIGRILNRFSKDQLTIDESIARTLGMFLNTFCQVVGSIIVIAWVSPFIILAMVPVGALFYFIQKYYLNSSRELTRLEGVSRSPIYAHFSETLAGVTTIRAFKDVARFVTENERLLDENQKCYYINISSNRWLAIRLEFLGACLVSCAVLYTVLARSRIEAGTAGLVITYALAITGNMNWMVRMSCDLEN | ||||||
Domain | 1344-1578 | ABC transporter 2 | ||||
Sequence: IVFKNLWLTYREGLDPVLRGINCTIEPKTKVGIVGRTGAGKSSLTQALFRLVEPLRGTIEIDGIDITELGLNPLRSRMAIIPQDPVLFAGSVRYNLDPFDQYDDHEIWEAIENAHLLKAIKDLDGGLDAMVQDGGDNFSVGQRQLLVIGRALLKKANIIVLDEASSSIDIASDALIQETIRTKFADCTVLTIAHRLGTIADSDKIMVLDKGELIEYDSPSELLKNQDSIYYSLVK |
Sequence similarities
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,593
- Mass (Da)178,339
- Last updated2005-05-24 v1
- ChecksumC1BC5D9F4A480A35
Features
Showing features for sequence conflict, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 61 | in Ref. 1; AAL85711 | ||||
Sequence: S → F | ||||||
Compositional bias | 816-845 | Polar residues | ||||
Sequence: MSHDEQQQQLQQQQAPDKSSDSNEQIGGGD | ||||||
Compositional bias | 876-902 | Polar residues | ||||
Sequence: SRSPSPSSNRNIDGDDIASGSILQTTR | ||||||
Sequence conflict | 1325 | in Ref. 1; AAL85711 | ||||
Sequence: E → K | ||||||
Sequence conflict | 1587 | in Ref. 1; AAL85711 | ||||
Sequence: D → N |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF474340 EMBL· GenBank· DDBJ | AAL85711.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAFI02000073 EMBL· GenBank· DDBJ | EAL64897.1 EMBL· GenBank· DDBJ | Genomic DNA |