Q54N47 · BCAT_DICDI
- ProteinBranched-chain-amino-acid aminotransferase
- GenebcaA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids378 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Catalytic activity
- L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamateThis reaction proceeds in the forward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | branched-chain-amino-acid transaminase activity | |
Molecular Function | L-isoleucine transaminase activity | |
Molecular Function | L-leucine transaminase activity | |
Molecular Function | L-leucine:2-oxoglutarate aminotransferase activity | |
Molecular Function | L-valine transaminase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | branched-chain amino acid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBranched-chain-amino-acid aminotransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionQ54N47
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000340236 | 1-378 | Branched-chain-amino-acid aminotransferase | |||
Sequence: MFGRFIRQYSTSKNIINVNELIVEKTKTPFQKYTDKTKLVFGKQFSDHMIEVQWTKEEGWGVPKISGYHNLSIPPSASVLHYALECFEGMKAYKDSNGKIRLFRPDQNMNRFLNSAKRICLPEFNKEAVIELIKKLCVLDKDWIPEGKGYSLYLRPTLIATQNSLGVGASNSALMFVIASPVGPYYPEGFKPVKLIADDQYVRAWAGGSGAFKLGSNYAPTIFPQLEAAKKGFSQVLWLLNDYVTEVGTMNMFVFWNNAQGEKELITPPLGDGTILPGVTRDSILKLTQQWGEFKITEKNFTMTELAKAIKEGRVFEAFGAGTAAIVSPIESISYKGENYSIPIDASLNCGPLTKRISDSIMAIQYGETNSDWSVIVD | ||||||
Modified residue | 213 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Proteomic databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length378
- Mass (Da)42,244
- Last updated2005-05-24 v1
- Checksum8011D40659CB65B0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAFI02000079 EMBL· GenBank· DDBJ | EAL64592.1 EMBL· GenBank· DDBJ | Genomic DNA |