Q54K67 · MANG_DICDI

Function

Catalytic activity

  • Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
    EC:3.2.1.24 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

110871002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site264Zn2+ (UniProtKB | ChEBI)
Binding site266Zn2+ (UniProtKB | ChEBI)
Active site376Nucleophile
Binding site376Zn2+ (UniProtKB | ChEBI)
Binding site579Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionalpha-mannosidase activity
Molecular Functioncarbohydrate binding
Molecular Functionmetal ion binding
Biological Processmannose metabolic process
Biological Processoligosaccharide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      manG
    • ORF names
      DDB_G0287577

Organism names

Accessions

  • Primary accession
    Q54K67

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003274861-1087Alpha-mannosidase G

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyl hydrolase 38 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,087
  • Mass (Da)
    123,691
  • Last updated
    2005-05-24 v1
  • Checksum
    32E15E3EA33F6CAA
MTSGNVMLKHQDVTIERIEKFLSDTYFVRENLYGKLISLKSSEAVKVKVSPKVEGISYKDAIQLEYKDTKIGESFGPSWTNYWFKVTIDVPTDWKDKTIHFIWNSSCEGLIWMNGIAIQGLIGGTWQDLREEYKLIENSKGGEHFEFYIEISCNGMFGVGKDGLINPCDPDRTFELTKAEIRVKNKEANELYMYLQMLYDVGKNFPKESLRKKQAIWVANDIINQCNVNDSRTFSKCIELAKKEFFSQHNSESQTRVWAVGHCHIDLCWLWSFEKTKEKCARSFSTQILYMDYYPQFKFTQSQAQAYQWTKENYPELYERIKEKVVTGQFIPTGGTWVEMDGNLPSGESFIRQFLYGQRFFEKEFGKKCTEFFLPDTFGYSAQLPQVIRHMGIENFITQKLSWNNLNKFPHSTFIWEGIDGSSVLTHFPPADTYNSQADVKEIVMSSSNNKDIDRCNESMLLYGNGDGGGGPTIPMIERLTILKDTAGIPKIEFSTPAQFFKQLEPHRSKLNKWVGELYFELHRGTYTSQATTKRGNRLCEIELHATEMLTSYCELFVEGFKSPNLSKLWQQVLLCQFHDALPGSSIQVCYEDILKIHQQVLVECKNIITQSMNHITGTLLKIDNLPTTSTTTSTTTTSTTECTKNSEFVLAFNANDFEISRVIEIPKSNKDIQAQYINAIQTSYNGLPLGTVSLPPNGFSAINISTSGDNRTINRKPGYPCTAIEKNDASGDILIDNQFISIVIGSNGRIKSLIEKSANREVIKQDGSLGNRLIIFDDTCLFWDAWDQEIFSLEKPLSILEGTCKIIENGPLRCVVQVHYDSKGLPSGNGSVNQTIIVHFNSARVDFETNVNWNEAHKLLRVDFDTNIRAKNANYEIQFGHIERPTHYNTSWDFARFEVVGHKWADLSEYDFGMALLNDCKYGYSTLGGRIGLSLLRSPKSPDDTCDMGSHKFTYSIYPHRGSLQSASVIKEGYSLNNNFYISETPFSLASTTHIDKTFISTNKEAIIVDTIKKAEDGTSFVVRVYESFGGATTFNFTSSILPIPFKSIIECNGLEEVNQSSKSYKFNDTIKINPFEIKTFRFISN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAFI02000102
EMBL· GenBank· DDBJ
EAL63688.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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