Q54H71 · ADPRH_DICDI

Function

function

Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site79Mg2+ 1 (UniProtKB | ChEBI)
Binding site80Mg2+ 1 (UniProtKB | ChEBI)
Binding site81Mg2+ 1 (UniProtKB | ChEBI)
Binding site109substrate
Binding site159substrate
Binding site348Mg2+ 2 (UniProtKB | ChEBI)
Binding site350Mg2+ 1 (UniProtKB | ChEBI)
Binding site350Mg2+ 2 (UniProtKB | ChEBI)
Binding site351Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionADP-ribosylarginine hydrolase activity
Molecular Functionmetal ion binding
Biological Processprotein modification process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ADP-ribosylhydrolase ARH1
  • EC number
  • Alternative names
    • ADP-ribose-L-arginine cleaving enzyme
    • [Protein ADP-ribosylarginine] hydrolase (ADP-ribosylarginine hydrolase)

Gene names

    • Name
      adprh
    • ORF names
      DDB_G0289675

Organism names

Accessions

  • Primary accession
    Q54H71

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003282091-392ADP-ribosylhydrolase ARH1

Proteomic databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region125-127Substrate
Region192-194Substrate
Region309-311Substrate
Region315-316Substrate

Sequence similarities

Belongs to the ADP-ribosylglycohydrolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    392
  • Mass (Da)
    44,362
  • Last updated
    2005-05-24 v1
  • Checksum
    B99C7063F05AB67C
MFHKFISTLTNKKITQTIMGTINKENIKPAMLLSAFGDACGYKNGIWEFEKSPSRIYEHYEYLGGYKNLKINKKDWRLSDDTIMHIATAIAITRPTNTDNESICKELAKAYIHSMEDMAGRAPGIQTINSVSLMTQTGMRSKVYQWNEIDFSDRAGGCGGSMRSMCIGFKYWSDEQLDTLIELSIESGRITHNNPVGFLGALVSALFASYAIRSIPPKTWPLKLMTEVMPKAREYLEKTSNSSNRNIENYEKGWNYFWNSWKSYLKLRQIPSNPDELKAANDKGIDYPVFPKDYSDYKVRENFYHSISFSGWGGSSGHDSCIIAYDALLGSADNWEEMIKRSVLHGGDNDSTGAIGCCWWGALYGFNGVPECNYEKIEYKSIIEGLAKEISN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAFI02000148
EMBL· GenBank· DDBJ
EAL62549.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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