Q54GZ0 · OMT9_DICDI
- ProteinO-methyltransferase 9
- Geneomt9
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids357 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 200 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 224 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 249 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 250 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 263 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Active site | 267 | Proton acceptor | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3,5-dichloro-THPH methyl transferase activity | |
Molecular Function | O-methyltransferase activity | |
Molecular Function | S-adenosylmethionine-dependent methyltransferase activity | |
Biological Process | biosynthetic process | |
Biological Process | methylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameO-methyltransferase 9
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Amoebozoa > Evosea > Eumycetozoa > Dictyostelia > Dictyosteliales > Dictyosteliaceae > Dictyostelium
Accessions
- Primary accessionQ54GZ0
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000367479 | 1-357 | O-methyltransferase 9 | |||
Sequence: MDSGLSTPQLPITNMNNEITTDWDKAMNLIMTCVSGHIHSRMFNIVMKLNICDILEDGPKSIKQVSDTIGMDENSCFRLLRYFVAHELFSEDKSNIGTFEKTSISTMFSSKGKLRPMGERYTHDLHYKMFESLPETFANGHSNATKSVGVNHFWELFDLHPQYKDLFNQTMKVYTEAAISNITQSKGIDFSQYDTVVDIGGNHGLLIGNLLEIYPTIKHGINFDLDVVINSSDQTLRYSHPRLTHIPGNFFESVPESDCYIMKFILHDWPTQDCVKILKTISKSMKPNAKIHLFEIIIDPRKGYSKYETYIDILMFQMVNAKERTLDEWKELFELADFKLERVVDDIKTGCMVVSKK |
Proteomic databases
Structure
Family & Domains
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length357
- Mass (Da)41,073
- Last updated2005-05-24 v1
- ChecksumE47308D2DB744BFF
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAFI02000149 EMBL· GenBank· DDBJ | EAL62512.1 EMBL· GenBank· DDBJ | Genomic DNA |