Q54CK9 · WASH1_DICDI

Function

function

Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentearly endosome
Cellular Componentearly phagosome
Cellular Componentpathogen-containing vacuole
Cellular Componentphagolysosome
Cellular Componentrecycling endosome
Cellular ComponentWASH complex
Molecular Functionactin binding
Molecular Functionalpha-tubulin binding
Molecular Functiongamma-tubulin binding
Biological Processactin filament polymerization
Biological Processactin nucleation
Biological ProcessArp2/3 complex-mediated actin nucleation
Biological Processdefense response to Gram-negative bacterium
Biological Processendocytic recycling
Biological Processexocytosis
Biological Processlysosomal transport
Biological Processphagosome reneutralization
Biological Processpositive regulation of endocytic recycling
Biological Processprotein secretion
Biological Processretrograde transport, endosome to Golgi
Biological Processsecretion of lysosomal enzymes

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    WAS protein family homolog DDB_G0292878

Gene names

    • ORF names
      DDB_G0292878

Organism names

Accessions

  • Primary accession
    Q54CK9

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003883661-472WAS protein family homolog DDB_G0292878

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias279-320Polar residues
Region279-472Disordered
Compositional bias321-358Pro residues
Domain382-401WH2
Compositional bias388-409Basic and acidic residues

Sequence similarities

Belongs to the WASH1 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    472
  • Mass (Da)
    50,922
  • Last updated
    2005-05-24 v1
  • Checksum
    46336D02070F89B8
MTTQIYQVPVVSNGLRETESILQIVDSLEKLEKVFNDMYSTISARVSHEKSRIDNVANRLNNAQHKVNQIVGSKQAITVFSSAKYPADKKWGDYVPIYSGKHKLPFKPSHYHGLNSEDSPIKKRPEDSYLDVNDLVFIEKSIDTTSKEVEVKEGLGRIPAQIPSVSNLLLFNTQENPYKKYSNTLDNLSGGDGGEDDYTIFGDQLSKKKRLGDAPVTVKDGDSRIDAENVKIGYEPGTFEIPVYNFPSILPLPNVAENITWAAESQSIAPSQKATLNLLPTYDNSNSGSAPVNQSSGGDNNVNNNNNNNNSNNSTGIMQPPQPTNAPPPPPPPPQSANAPPPPPPPPVSAPPPFNPPSVNSNNDDDDDDDDDNGGGGGPGGAIGDLLADIRRGHKNRLKKADVGGDNGDGEDNKPPPVSDGGGGLMGDLFKKLALRRQSIATTKSTKKQSKSKKEDTDDQDGESDTDSSEWE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias279-320Polar residues
Compositional bias321-358Pro residues
Compositional bias388-409Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAFI02000197
EMBL· GenBank· DDBJ
EAL60988.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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