Q541Z2 · Q541Z2_MOUSE

  • Protein
    Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
  • Gene
    Fnta
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentCAAX-protein geranylgeranyltransferase complex
Cellular Componentmicrotubule associated complex
Cellular Componentplasma membrane
Cellular Componentprotein farnesyltransferase complex
Molecular Functionalpha-tubulin binding
Molecular Functionmicrotubule binding
Molecular Functionprotein farnesyltransferase activity
Molecular Functionprotein geranylgeranyltransferase activity
Biological Processneuromuscular junction development
Biological Processpositive regulation of tubulin deacetylation
Biological Processskeletal muscle acetylcholine-gated channel clustering

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
  • EC number
  • Alternative names
    • CAAX farnesyltransferase subunit alpha
    • FTase-alpha
    • Ras proteins prenyltransferase subunit alpha
    • Type I protein geranyl-geranyltransferase subunit alpha

Gene names

    • Name
      Fnta

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q541Z2

Organism-specific databases

PTM/Processing

Proteomic databases

PTM databases

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Region1-55Disordered
Compositional bias17-34Pro residues
Coiled coil320-354

Sequence similarities

Belongs to the protein prenyltransferase subunit alpha family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    377
  • Mass (Da)
    44,013
  • Last updated
    2005-05-24 v1
  • Checksum
    F3D60B9899F36D66
MAATEGVGESAAGGEPGQPEQPPPPPPPPPAQQPQEEEMAAEAGEAAASPMDDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKDPSQELEFIADILSQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVISNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSRYPNLLNQLLDLQPSHSSPYLIAFLVDVYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHCRESDIPASV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias17-34Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK010744
EMBL· GenBank· DDBJ
BAB27154.1
EMBL· GenBank· DDBJ
mRNA
AK090346
EMBL· GenBank· DDBJ
BAC41179.1
EMBL· GenBank· DDBJ
mRNA
AK153252
EMBL· GenBank· DDBJ
BAE31843.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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