Q53SN7 · Q53SN7_HUMAN
- ProteinAlkylglycerone-phosphate synthase
- GeneAGPS
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids183 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Catalytic activity
- a 1-acylglycerone 3-phosphate + a long chain fatty alcohol = 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H+
Cofactor
Pathway
Glycerolipid metabolism; ether lipid biosynthesis.
Features
Showing features for binding site, site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | alkylglycerone-phosphate synthase activity | |
Molecular Function | FAD binding | |
Biological Process | ether lipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkylglycerone-phosphate synthase
- EC number
- Short namesAlkyl-DHAP synthase
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ53SN7
Subcellular Location
PTM/Processing
Proteomic databases
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-52 | FAD-binding PCMH-type | ||||
Sequence: VVHIKMVTPRGIIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPV |
Sequence similarities
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length183
- Mass (Da)20,429
- Last updated2005-05-24 v1
- Checksum8BB38BA310BDC0C3
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: V | ||||||
Non-terminal residue | 183 | |||||
Sequence: R |