Q53P85 · CDPKO_ORYSJ

Function

function

May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity).
Possesses calcium-dependent protein kinase activity in vitro (PubMed:16255173).

Catalytic activity

Activity regulation

Activated by calcium. Autophosphorylation may play an important role in the regulation of the kinase activity.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site53-61ATP (UniProtKB | ChEBI)
Binding site76ATP (UniProtKB | ChEBI)
Active site171Proton acceptor
Binding site361Ca2+ 1 (UniProtKB | ChEBI)
Binding site363Ca2+ 1 (UniProtKB | ChEBI)
Binding site365Ca2+ 1 (UniProtKB | ChEBI)
Binding site367Ca2+ 1 (UniProtKB | ChEBI)
Binding site372Ca2+ 1 (UniProtKB | ChEBI)
Binding site397Ca2+ 2 (UniProtKB | ChEBI)
Binding site399Ca2+ 2 (UniProtKB | ChEBI)
Binding site401Ca2+ 2 (UniProtKB | ChEBI)
Binding site403Ca2+ 2 (UniProtKB | ChEBI)
Binding site408Ca2+ 2 (UniProtKB | ChEBI)
Binding site433Ca2+ 3 (UniProtKB | ChEBI)
Binding site435Ca2+ 3 (UniProtKB | ChEBI)
Binding site437Ca2+ 3 (UniProtKB | ChEBI)
Binding site444Ca2+ 3 (UniProtKB | ChEBI)
Binding site467Ca2+ 4 (UniProtKB | ChEBI)
Binding site469Ca2+ 4 (UniProtKB | ChEBI)
Binding site471Ca2+ 4 (UniProtKB | ChEBI)
Binding site473Ca2+ 4 (UniProtKB | ChEBI)
Binding site478Ca2+ 4 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent protein serine/threonine kinase activity
Molecular Functioncalcium/calmodulin-dependent protein kinase activity
Molecular Functioncalmodulin binding
Molecular Functionhistone H2AS1 kinase activity
Molecular Functionprotein serine kinase activity
Biological Processintracellular signal transduction
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Calcium-dependent protein kinase 24
  • EC number
  • Short names
    OsCDPK24
    ; OsCPK24
  • Alternative names
    • Calcium-dependent protein kinase OsCDPK14

Gene names

    • Name
      CPK24
    • ORF names
      OsJ_33123
    • Ordered locus names
      Os11g0171500
      , LOC_Os11g07040

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q53P85
  • Secondary accessions
    • Q6YIH2

Proteomes

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00004375661-513UniProtCalcium-dependent protein kinase 24
Modified residue (large scale data)211PTMeXchangePhosphoserine
Modified residue (large scale data)430PTMeXchangePhosphoserine
Modified residue (large scale data)495PTMeXchangePhosphothreonine
Modified residue (large scale data)499PTMeXchangePhosphoserine

Proteomic databases

Expression

Tissue specificity

Expressed in roots.

Induction

By N-acetylchitooligosaccharide elicitor (PubMed:12956525).
Induced by UV-C (PubMed:24035516).

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-33Disordered
Domain47-305Protein kinase
Region311-341Autoinhibitory domain
Domain348-383EF-hand 1
Domain384-419EF-hand 2
Domain420-455EF-hand 3
Domain458-489EF-hand 4

Domain

There are 3 contiguous domains conserved in the CDPK subfamily: a kinase domain, an autoinhibitory (junction) domain and a calmodulin-like domain. The autoinhibitory domain (311-341) inactivates kinase activity under calcium-free conditions.

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    513
  • Mass (Da)
    56,672
  • Last updated
    2005-05-24 v1
  • Checksum
    63EF52BB256FE0E3
MQPDPSGSGGDGNANAKAKLAPPPVTAAGGRPVSVLPHKTANVRDHYRIGKKLGQGQFGTTYLCVDKASGGEFACKSIPKRKLLCREDYEDVWREIQIMHHLSEHPNVVRIRGAYEDALFVHIVMELCAGGELFDRIVAKGHYTERAAAQLIRTIVAVVEGCHSLGVMHRDLKPENFLFASAAEDAPLKATDFGLSMFYKPGDKFSDVVGSPYYVAPEVLQKCYGPESDVWSAGVILYILLCGVPPFWAETEAGIFRQILRGKLDFESEPWPSISDSAKDLVRNMLCRDPTKRLTAHEVLCHPWIVDDAVAPDKPIDSAVLSRLKHFSAMNKLKKMALRVIAESLSEEEIGGLKELFKMIDTDDSGTITFDELKEGLKRVGSELTEHEIQALMEAADIDNSGTIDYGEFIAATLHMNKLEREENLVSAFSFFDKDGSGFITIDELSQACREFGLDDLHLEDMIKDVDQNNDGQIDYSEFTAMMRKGNAGGAGRRTMRNSLQLNLGEILNPSNS

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict52in Ref. 1; AAN41657

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY144497
EMBL· GenBank· DDBJ
AAN41657.1
EMBL· GenBank· DDBJ
mRNA
AC128643
EMBL· GenBank· DDBJ
AAX95085.1
EMBL· GenBank· DDBJ
Genomic DNA
DP000010
EMBL· GenBank· DDBJ
ABA91635.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008217
EMBL· GenBank· DDBJ
BAF27709.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014967
EMBL· GenBank· DDBJ
BAT12871.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000148
EMBL· GenBank· DDBJ
EAZ17585.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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