CD34 staining in megakaryocytes was associated with p53 expression (p=0.0166). CD34 and p53 expression were associated to worse overall survival in patients (p=0.0281). CONCLUSION: The presence of CD34 in megakaryocytes is associated with p53 expression and an adverse prognosis for Myelodysplastic syndromes (MDS) patients.
tumors harboring TP53 mutations which can impair epithelial function have a unique bacterial consortium that is higher in relative abundance in smoking-associated tumors.
The expression levels of ER CD34 and p53 in breast cancer tissue can be evaluated by color Doppler ultrasonographic features which is conducive to assessing the prognosis of these patients.
these results demonstrated that the messenger RNA expression levels of p53 and p21 may have a relationship with the changes in telomere length induced by omethoate and provided strong evidence for the mechanism of canceration induced by poison.
Since most ATCs were reported to carry the mutated form of p53 while PTCs carry mostly the wild-type form of p53 it is likely that FUCA1 expression levels are regulated at least in part by the p53 status in thyroid cancers.
Our data showed that relative TP53 mRNA expression was not significantly altered in both tissues exposed to lasers. For ATM relative mRNA expression in skin tissue was not significantly altered but in muscle tissue laser exposure increased relative ATM mRNA expression. Low-level red and infrared laser radiations alter ATM mRNA expression related to DNA stability in skeletal muscle tissue.
The expression of p53 fulllength transcript and Delta133p53 isoforms alpha beta and gamma transcripts MDM2 and p21 transcripts were determined by reverse transcriptionquantitative polymerase chain reaction in total RNA isolated from 17 lung carcinoma specimens and 17 corresponding adjacent noncancerous tissues.
We found the higher expression of P53 isoforms in inverted papilloma and squamous cell carcinomas compared to benign papillomas suggesting their role in local aggressiveness and malignant proliferation in head-neck lesions.
The investigation of p53 and Ki-67 expression is useful in identifying highly proliferative forms of salivary tumors with aggressive potential of evolution.
133p53 and p53beta which are possible indicators for the diagnosis and biological therapy of gastric carcinoma were expressed differentially in different gastric tissues
p53 immunoexpression differs in SCC and VC suggesting different pathogenesis and it may have some utility as an adjunct to morphology to differentiate between the 2
Data indicate that high expression of p16 and p53 and low expression of p27 were related with the distinguishing of papillary thyroid carcinoma (PTC) from benign lesions.
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