Q52KB5 · ZBT24_DANRE
- ProteinZinc finger and BTB domain-containing protein 24
- Genezbtb24
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids672 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
May be involved in BMP2-induced transcription.
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 140-152 | A.T hook 1 | ||||
Sequence: KRKRGRPKKNQDL | ||||||
DNA binding | 223-235 | A.T hook 2 | ||||
Sequence: PGKRGRRRKYPDT |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | nucleoplasm | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | DNA-binding transcription repressor activity, RNA polymerase II-specific | |
Molecular Function | metal ion binding | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Biological Process | negative regulation of transcription by RNA polymerase II | |
Biological Process | regulation of cytokine production | |
Biological Process | regulation of DNA-templated transcription | |
Biological Process | regulation of immune system process | |
Biological Process | urogenital system development |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameZinc finger and BTB domain-containing protein 24
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ52KB5
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000047737 | 1-672 | Zinc finger and BTB domain-containing protein 24 | |||
Sequence: MSALPPSSSSPAVLALHSATHKDTILHKFDTLRRSELLCDITLIVEDVHFKAHKALLAASSEYFSALFTAEEQVSQSLYKLDGMTANTFSSVLEFMYSAVVLVDESSSEQLMEMARFLVIPDLIKAHEDLQAVDEHMQVKRKRGRPKKNQDLSQKENPESELQAQTSSEIQEVNEEPASPATDGSDGEFNPREERRREGKRKIKQPIRLKGFRMDDLMEGKEPGKRGRRRKYPDTEARCEECGKVFKSHLFLKIHQRTHTGEKPFRCSVCGKEFTQKHTLLVHQRMHTGEKPYICTVCSKALSTKHSLLEHMNLHTENKLFTCEECGKSFSQQRQLKSHNRVHTGKGLPECAECHHKFMDAAQLKKHLRTHTGEKPFTCEICGKCFTAKSTLQTHIRIHRGEKPYVCKVCDKTFSDPSARRRHEVSHTGKKTFSCSICKVSFARKDNLKAHIKTHNKENPPAQAESTDKPPQSAPEQQEQEQQQQQQTSGDKELHSILQLQPFQLPAHGEQEIQLLVTGENLSLDQEQSISIITSEDTEQSLALLTQPSGHVQNLAVVTPDGNAQIQTISVLGGEVNGGDPEQMHVITLSKEAMEQLQVHHGAPQQLQVIHQLSEEQTGPVAGIHISGQSGQAISISQTTEQIPSDQIQGQTFQIQAGTVSYLYTTSMNPQN |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 39-105 | BTB | ||||
Sequence: CDITLIVEDVHFKAHKALLAASSEYFSALFTAEEQVSQSLYKLDGMTANTFSSVLEFMYSAVVLVDE | ||||||
Region | 136-208 | Disordered | ||||
Sequence: HMQVKRKRGRPKKNQDLSQKENPESELQAQTSSEIQEVNEEPASPATDGSDGEFNPREERRREGKRKIKQPIR | ||||||
Compositional bias | 156-175 | Polar residues | ||||
Sequence: ENPESELQAQTSSEIQEVNE | ||||||
Zinc finger | 237-259 | C2H2-type 1 | ||||
Sequence: ARCEECGKVFKSHLFLKIHQRTH | ||||||
Zinc finger | 265-287 | C2H2-type 2 | ||||
Sequence: FRCSVCGKEFTQKHTLLVHQRMH | ||||||
Zinc finger | 293-315 | C2H2-type 3 | ||||
Sequence: YICTVCSKALSTKHSLLEHMNLH | ||||||
Zinc finger | 321-343 | C2H2-type 4 | ||||
Sequence: FTCEECGKSFSQQRQLKSHNRVH | ||||||
Zinc finger | 349-371 | C2H2-type 5 | ||||
Sequence: PECAECHHKFMDAAQLKKHLRTH | ||||||
Zinc finger | 377-399 | C2H2-type 6 | ||||
Sequence: FTCEICGKCFTAKSTLQTHIRIH | ||||||
Zinc finger | 405-427 | C2H2-type 7 | ||||
Sequence: YVCKVCDKTFSDPSARRRHEVSH | ||||||
Zinc finger | 433-455 | C2H2-type 8 | ||||
Sequence: FSCSICKVSFARKDNLKAHIKTH | ||||||
Region | 453-492 | Disordered | ||||
Sequence: KTHNKENPPAQAESTDKPPQSAPEQQEQEQQQQQQTSGDK | ||||||
Compositional bias | 459-492 | Polar residues | ||||
Sequence: NPPAQAESTDKPPQSAPEQQEQEQQQQQQTSGDK |
Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length672
- Mass (Da)75,410
- Last updated2005-05-24 v1
- Checksum2C8F21121BF6FD1B
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
E7F443 | E7F443_DANRE | zbtb24 | 678 |
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 156-175 | Polar residues | ||||
Sequence: ENPESELQAQTSSEIQEVNE | ||||||
Sequence conflict | 166 | in Ref. 2; AAI63252 | ||||
Sequence: T → S | ||||||
Compositional bias | 459-492 | Polar residues | ||||
Sequence: NPPAQAESTDKPPQSAPEQQEQEQQQQQQTSGDK | ||||||
Sequence conflict | 475 | in Ref. 2; AAI63252 | ||||
Sequence: P → PEQQ |
Keywords
- Technical term