Q51520 · PHZF_PSECL
- ProteinTrans-2,3-dihydro-3-hydroxyanthranilate isomerase
- GenephzF
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids278 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Isomerase that catalyzes the condensation of two molecules of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known.
Catalytic activity
- (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate = (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate
Pathway
Antibiotic biosynthesis; phenazine biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 45 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity | |
Biological Process | phenazine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTrans-2,3-dihydro-3-hydroxyanthranilate isomerase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ51520
- Secondary accessions
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000162381 | 1-278 | Trans-2,3-dihydro-3-hydroxyanthranilate isomerase | |||
Sequence: MHHYVIIDAFASAPLEGNPVTVFFDADDLSATQMQRIAREMNLSETTFVLKPRNCGDALIRIFTPVNELPFAGHPLLGTAIALGAHTDNHRLFLETQMGTIAFELERQNGSVVAASMDQPIPTWTALGRDVELLKALGISDSTFPIEIYHNGPRHVFVGLPSIAALSALHPDHRALSSFHDMAINCFAGAGRRWRSRMFSPAYGVVEDAATGSAAGPLAIHLARHGQIEFGQQIEILQGVEIGRPSLMFARAEGRADQLTRVEVSGNGVTFGRGTIVL |
Structure
Sequence
- Sequence statusComplete
- Length278
- Mass (Da)30,118
- Last updated2001-09-26 v2
- Checksum88BB229A45F04C06
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 2 | in Ref. 1; AAB00331 | ||||
Sequence: H → E | ||||||
Sequence conflict | 13 | in Ref. 1; AAB00331 | ||||
Sequence: A → V | ||||||
Sequence conflict | 21 | in Ref. 1; AAB00331 | ||||
Sequence: T → A | ||||||
Sequence conflict | 32 | in Ref. 1; AAB00331 | ||||
Sequence: T → E | ||||||
Sequence conflict | 80 | in Ref. 1; AAB00331 | ||||
Sequence: A → D | ||||||
Sequence conflict | 86 | in Ref. 1; AAB00331 | ||||
Sequence: H → R | ||||||
Sequence conflict | 113 | in Ref. 1; AAB00331 | ||||
Sequence: V → I | ||||||
Sequence conflict | 131 | in Ref. 1; AAB00331 | ||||
Sequence: V → A | ||||||
Sequence conflict | 177 | in Ref. 1; AAB00331 | ||||
Sequence: S → Y | ||||||
Sequence conflict | 269 | in Ref. 1; AAB00331 | ||||
Sequence: V → I |