Q50960 · Q50960_NEIGO
- ProteinProbable peptidoglycan D,D-transpeptidase PenA
- GenepenA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids582 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
Catalytic activity
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 310 | Acyl-ester intermediate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | penicillin binding | |
Molecular Function | peptidoglycan glycosyltransferase activity | |
Molecular Function | serine-type D-Ala-D-Ala carboxypeptidase activity | |
Biological Process | cell wall organization | |
Biological Process | division septum assembly | |
Biological Process | FtsZ-dependent cytokinesis | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | proteolysis | |
Biological Process | regulation of cell shape | |
Biological Process | response to antibiotic |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable peptidoglycan D,D-transpeptidase PenA
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria
Accessions
- Primary accessionQ50960
- Secondary accessions
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 28-48 | Helical | ||||
Sequence: ISFVLMAMAVLFACLIARGLY |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 71-220 | Penicillin-binding protein dimerisation | ||||
Sequence: LPATRGTVSDRNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFVFEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDS | ||||||
Domain | 263-558 | Penicillin-binding protein transpeptidase | ||||
Sequence: GTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKALDAGKTDLNERLNTQPYKIGPSPVRDDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGETAGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPLSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEPGGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHVATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIM |
Sequence similarities
Belongs to the transpeptidase family. FtsI subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length582
- Mass (Da)63,765
- Last updated1996-11-01 v1
- Checksum241FBEF088160ECF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB727732 EMBL· GenBank· DDBJ | BAM21191.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727733 EMBL· GenBank· DDBJ | BAM21192.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727742 EMBL· GenBank· DDBJ | BAM21201.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727752 EMBL· GenBank· DDBJ | BAM21211.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727758 EMBL· GenBank· DDBJ | BAM21217.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727765 EMBL· GenBank· DDBJ | BAM21224.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB727766 EMBL· GenBank· DDBJ | BAM21225.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X59632 EMBL· GenBank· DDBJ | CAA42191.1 EMBL· GenBank· DDBJ | Genomic DNA |