Q4WHP3 · STE20_ASPFU

Function

function

MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.

Catalytic activity

Features

Showing features for binding site, active site.

1815100200300400500600700800
TypeIDPosition(s)Description
Binding site540-548ATP (UniProtKB | ChEBI)
Binding site563ATP (UniProtKB | ChEBI)
Active site653Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentincipient cellular bud site
Cellular Componentmating projection tip
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionhistone H2BS14 kinase activity
Molecular Functionprotein serine kinase activity
Biological Processbipolar cellular bud site selection
Biological Processbudding cell apical bud growth
Biological Processinvasive growth in response to glucose limitation
Biological Processnegative regulation of gene expression
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processosmosensory signaling pathway via Sho1 osmosensor
Biological Processpheromone-dependent signal transduction involved in conjugation with cellular fusion
Biological Processpositive regulation of apoptotic process
Biological Processpseudohyphal growth
Biological Processregulation of exit from mitosis
Biological Processsignal transduction involved in filamentous growth
Biological Processsterol import
Biological Processstress granule assembly
Biological Processvacuole inheritance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase ste20
  • EC number

Gene names

    • Name
      ste20
    • ORF names
      AFUA_2G04680

Organism names

Accessions

  • Primary accession
    Q4WHP3

Proteomes

Organism-specific databases

Subcellular Location

Phenotypes & Variants

Miscellaneous

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002376261-815Serine/threonine-protein kinase ste20

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-42Polar residues
Region1-160Disordered
Compositional bias49-117Polar residues
Region173-200Disordered
Compositional bias182-198Basic and acidic residues
Domain223-236CRIB
Region300-513Disordered
Compositional bias302-324Polar residues
Compositional bias355-384Pro residues
Compositional bias388-496Polar residues
Domain534-785Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    815
  • Mass (Da)
    89,671
  • Last updated
    2007-05-29 v2
  • Checksum
    6F3C54CF80285724
MSNDGFSSLKFRRTSSKLQKDPPSVSSRILRSQQSNTSLKRHPSAPVHPRSSVTGSREHSRTRSNAYGSSSSSLEQHSGGPSPVLAGGDSNNSFSSKSRPGRFSFNTDPSSDELTGSPFDSRGMLSALEENTAESEKSPPPQPPTLRSYHTSPDSRGLRQSASFTALQNRMDTFTQKSENDQSTNTKRHSDEANGTKVFGRSKKSSFSSFVNSMLGSPRGIKISAPENPVHVTHVGYDNQTGQFTGLPKEWQRLLQENGISKKEQEEHPQTMVDIMRFYEKNARGDDEVWHKFDHAYAHHQPTANTPGSQRNSPPTSPRFPQNHEGSFENPRAPPPIPRGAPAATQAMSPPIGGLVPSRAPPKPPAPANMIPARPAPQPPVARPPQDAYANQFSTPPISESEPLPSEAQRSRSNSKTNGAQPQWAQPGAIASPAQYQQQQEQAMAAAQQAIVQNQLERSRSQRQQQSRGPEPKQPTQMGHSQHANDHTTALQSPQKAQPVPAARPRQRARQSNAVDVRARLLAICTPGDPTKLYYNLNKIGQGASGGVYTAYQHGTNNCVAIKQMNLDLQPKKELIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRETLNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQINDSQNKRNTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASAHDLLMHPFMSLCSPLTHLAPLVKAARLSRAQEKAQKGGA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-42Polar residues
Compositional bias49-117Polar residues
Compositional bias182-198Basic and acidic residues
Compositional bias302-324Polar residues
Compositional bias355-384Pro residues
Compositional bias388-496Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHF01000008
EMBL· GenBank· DDBJ
EAL87562.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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