Q4WDF1 · EPL1_ASPFU

Function

function

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentNuA4 histone acetyltransferase complex
Cellular Componentnucleus
Cellular Componentpiccolo histone acetyltransferase complex
Biological ProcessDNA repair
Biological Processregulation of transcription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Enhancer of polycomb-like protein 1

Gene names

    • Name
      epl1
    • ORF names
      AFUA_6G04530

Organism names

Accessions

  • Primary accession
    Q4WDF1

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002141561-582Enhancer of polycomb-like protein 1

Interaction

Subunit

Component of the NuA4 histone acetyltransferase complex.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for coiled coil, region, compositional bias.

TypeIDPosition(s)Description
Coiled coil238-295
Region323-351Disordered
Coiled coil352-385
Region539-582Disordered
Compositional bias545-567Polar residues

Sequence similarities

Belongs to the enhancer of polycomb family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    582
  • Mass (Da)
    66,417
  • Last updated
    2005-07-05 v1
  • Checksum
    2629F25A7AB902D5
MGRTRPKKLTSKASIPIVREHEIDIIDDEVQNALQQVETGVEKAEESEFHLQAAISATAQGKVNEAHIPTPETVLSNLRYDELYPPIFSQPATYIRFSSTIEDCCGCPYNMTEEDDVFFKIMNEKREPSNRITEDQFEEVMYFFEETAQTKQPFAAVDSPPVLSFAEMQDSMDATVEESVKCFAKDIYEHWKLRRIATGNRPLLPSLKFETGQDTDDTDPYVCFRRREVRQIRKTRGRDAQSADKLRRLRKELEDARQLVALVRQRELARKEMLSMERQIFLQRSEVKEMKRKLNIKDDDEDLINQKVTSIPARLPHAFANLPEQPKKKPAEAPAAQRPTAPQIRMPQKPGTQAADDMQLLEDVQAEKENEILRDIKQNIAKHIKWNEGYVDYTRAPLSPPPEKTFQAAFRPAITTQLPTPPSSDSSDNMMLESALDTANSLSFRDKLVPRTWEMNEDTCRIPSFRRRIGRGGRLMIDRRNMASRCRIEMDPLKADRFKYDREDSDDESEFECDPYDVQIMQHRAIMAAKARDQAAAAAQAHAQAQAQKRLQAEQTTTNNGPPNIGHTMGSNPGPGAVASTS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias545-567Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHF01000012
EMBL· GenBank· DDBJ
EAL85587.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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