Q4VDB0 · Q4VDB0_DANRE

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcation channel complex
Cellular Componentplasma membrane
Molecular Functioninositol 1,4,5 trisphosphate binding
Molecular Functionstore-operated calcium channel activity
Biological Processcalcium ion transmembrane transport
Biological Processregulation of cytosolic calcium ion concentration
Biological Processsingle fertilization

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Transient receptor potential cation channel subfamily C member 2b
    • Transient receptor potential channel C2

Gene names

    • Name
      trpc2b
    • Synonyms
      trpc2
      , trpc2a

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    Q4VDB0

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane335-357Helical
Transmembrane369-388Helical
Transmembrane408-426Helical
Transmembrane438-463Helical
Transmembrane542-567Helical
Transmembrane579-600Helical
Transmembrane607-628Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain174-236Transient receptor ion channel
Compositional bias801-825Basic and acidic residues
Region801-847Disordered
Region861-888Disordered
Compositional bias869-885Basic and acidic residues
Region926-961Disordered
Compositional bias933-955Acidic residues
Region1109-1140Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,140
  • Mass (Da)
    129,923
  • Last updated
    2005-07-05 v1
  • Checksum
    C8B8A782D4C62AA3
MESLTPDQWREIVNKKFRFPPELLGAIREGNLNLVSSLLKTGDGIIRQLDDSEDRQWREALNLSIRLGNEDTMASLLQGVKFDFRQIHEALLVAVDTNQPRVVKRLLDRLDQEKGNKMDVRSFSMAIFDHSIDDSQFAPGVTPLTLACQKDLYDIVTMLNQKGHEIPWPHKISCACLECTNGRQYDLLKFSLSRINTYRGIASRAYLSITAEDAMLSAFRLSRDLRKLSKKEPEFKPQYLSLEQVCQEFAVELLGMCRNQSEVTTILNSCGDRDEDSEDELDHQTFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLSGWRGSRTSWKLLVSFGIFLTMPFLCLIYWIAPKSKLGKILKIPVIKFLLHSASYMWFLITLLGESIAMEVYRESFATRQHTILHNSFHMVWVVGFFWFECKEVWIEGLRSYFLDWWNCLDVMVLSMYLASFALRLVIMLKVHFLCQLQDNQDECVYFTETMRDQWHQEDPQFISEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMMRFMFILVIIGTAFLCGINNIYVPYIISPNLGKLNETFSFLFWTMFGMADQTYVDMPAFALAELVGRILYGIYTLIIVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTMPVPFNIIPSPKAVFYLLRGIVKRICCCCFNCNSAPDYPPLTSMKDEGGSGENRIPYRQQVIRALVQRYIESARREFEETKRKDVGNRITELSKVIGHLHTEMKQIHSNLFNYSGNTKADPSGDSSFLGKYILGAKNNFKDFNNERRAPPLQETVRHLEPAETNEEPEEERKEEQNAEEQIDNTLQTGNDDANKIVIEIESSPDAESGNAADKMEKAKEGTDLNGDVEESNGDVVEIISEGFKFNFGQTNLVSFLSKRIEEKLEKTVKDNEEELDGGETDVSGDVEESNEASEDAEVVSEENKFELNQTSMVSFLAKRFEEKLGGNFKENMEELNAGGADVEESNRASENANEDAEVVIYGIKFDLNQTSMVNFLTKRIEEKLEENFTENMEELNAGGADVEESNGASENANEDAEVVIYGIKFDLNQTSMVNFLTKRIEEKLDRTFSFTEKQASSPTGSNISQDTGFGSQEFNPSAGSP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias801-825Basic and acidic residues
Compositional bias869-885Basic and acidic residues
Compositional bias933-955Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY974804
EMBL· GenBank· DDBJ
AAY42077.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp