Q4UW52 · SYFB_XANC8
- ProteinPhenylalanine--tRNA ligase beta subunit
- GenepheT
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids791 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H+ + L-phenylalanyl-tRNA(Phe)
Cofactor
Note: Binds 2 magnesium ions per tetramer.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 453 | Mg2+ (UniProtKB | ChEBI); shared with alpha subunit | ||||
Sequence: D | ||||||
Binding site | 459 | Mg2+ (UniProtKB | ChEBI); shared with alpha subunit | ||||
Sequence: D | ||||||
Binding site | 462 | Mg2+ (UniProtKB | ChEBI); shared with alpha subunit | ||||
Sequence: E | ||||||
Binding site | 463 | Mg2+ (UniProtKB | ChEBI); shared with alpha subunit | ||||
Sequence: E |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | phenylalanine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | phenylalanyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhenylalanine--tRNA ligase beta subunit
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas
Accessions
- Primary accessionQ4UW52
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000232098 | 1-791 | Phenylalanine--tRNA ligase beta subunit | |||
Sequence: MKFSENWLRSHVPIQASREELAATLTAIGLEVEAVTPLGDALGQVVVARIIAAVRHPEADRLQVCSVDAGQGELLQIVCGAPNARAGLVAPLALVGAQIGELTIKAAKLRGVASNGMLCSAKELGLDSDASGLFELPDDAPVGQALAEYLGLPDASIEIKLTPNRADCFSVRGIAFDVAAACASEVAAFDAAAVAPVSTRTLAVELNAGSEAPRYCGRVIEGIDPAATTPVWMAERLRRSGVRPVSLLVDITQYVMLELGQPMHAFDLDTLHGPVGVRRSRAGEQLALLDGREVTLDDSFLTITDADRPVALAGLMGGLDTRVTNTTRNVFLESAYFDPAAIMGRGRKLGLHTDAGHRFERGVDPALAPQAIEVATRLVLELAGGMPGPVVDAALPHHLPQPASILLRRARIARVLGIQIDDADVARILTALGMHVEAAADGWQVTAPSRRFDIAIEEDLIEELARIHGYDRVPTTLPGGASRIAMPSETQLDELSVRRQLVARELQETINYAFVDAALLERWQLTDGVVPLANPLSAELAVMRPRLLPGLVATLGRNVARQVGRVRLFELGKVFSAAGPGDAPVESQQVAAAVCGDALALQWGEPARKVDFHDLKGDLLALAAASGAVLEFQPSTQPFGHPGRSADIYRDGVCIGWIGQVHPRLAKSLDIDVDVIAFELQLAPLVKRALPRAGELSRYPSMRRDLAFLVPDAVSWAALSASVRTSVGPLLREVQLFDRYVGQGVEPGFKSLAMGLILQDNSRTLTDRDVDAVVADVVAVIEREHRARIRG |
Interaction
Subunit
Tetramer of two alpha and two beta subunits.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 39-147 | tRNA-binding | ||||
Sequence: GDALGQVVVARIIAAVRHPEADRLQVCSVDAGQGELLQIVCGAPNARAGLVAPLALVGAQIGELTIKAAKLRGVASNGMLCSAKELGLDSDASGLFELPDDAPVGQALA | ||||||
Domain | 400-475 | B5 | ||||
Sequence: PQPASILLRRARIARVLGIQIDDADVARILTALGMHVEAAADGWQVTAPSRRFDIAIEEDLIEELARIHGYDRVPT | ||||||
Domain | 697-790 | FDX-ACB | ||||
Sequence: SRYPSMRRDLAFLVPDAVSWAALSASVRTSVGPLLREVQLFDRYVGQGVEPGFKSLAMGLILQDNSRTLTDRDVDAVVADVVAVIEREHRARIR |
Sequence similarities
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length791
- Mass (Da)84,353
- Last updated2005-07-05 v1
- Checksum61E1481C61B39093
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000050 EMBL· GenBank· DDBJ | AAY48721.1 EMBL· GenBank· DDBJ | Genomic DNA |