Q4A6T7 · TRMB_MYCS5
- ProteintRNA (guanine-N(7)-)-methyltransferase
- GenetrmB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids205 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.
Catalytic activity
- guanosine46 in tRNA + S-adenosyl-L-methionine = N7-methylguanosine46 in tRNA + S-adenosyl-L-homocysteine
Pathway
tRNA modification; N7-methylguanine-tRNA biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 34 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 59 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 86 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 107 | ||||
Binding site | 107 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 111 | substrate | |||
Binding site | 144 | substrate | |||
Binding site | 182-185 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | tRNA methyltransferase complex | |
Molecular Function | tRNA (guanine(46)-N7)-methyltransferase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(7)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mycoplasmoidales > Metamycoplasmataceae > Mycoplasmopsis
Accessions
- Primary accessionQ4A6T7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000229176 | 1-205 | tRNA (guanine-N7-)-methyltransferase | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 113-118 | Interaction with RNA | |||
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length205
- Mass (Da)24,346
- Last updated2005-09-13 v1
- Checksum22B1EFC945C3AF06
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE017245 EMBL· GenBank· DDBJ | AAZ43534.1 EMBL· GenBank· DDBJ | Genomic DNA |