Q4A1D7 · Q4A1D7_GIBFU

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site54For GATase activity
Binding site1185[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1191[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1196[3Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionglutamate synthase (NADH) activity
Molecular Functioniron ion binding
Biological Processglutamine metabolic process
Biological ProcessL-glutamate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • Name
      gltA

Organism names

Accessions

  • Primary accession
    Q4A1D7

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain54-463Glutamine amidotransferase type-2
Region962-983Disordered

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,114
  • Mass (Da)
    233,799
  • Last updated
    2005-09-13 v1
  • Checksum
    9537D294D80D59BB
MGLNEDFDDRHIQTEAEQQPYIPYEYQTENNDSWAGALPVKQGLYDPSYEKDACGVGFACHIKGKPSHKIVSDARNLLCNMTHRGAVGSDARDGDGAGVMTSIPHRFFIKNFEKEEDIKLPPLGQYAVGNLFFKPDEETLQESKRQLEDVAESLGLRVLGWRRPPVDSTLLGPAAKSREPIIAQPFVVLASAYGTGNAPEMTDPEKFDERLFERQLYILRKRATQSIGLHNWFYLCSLSNKNIVYKGQLAPVQVYSYYHDLVNADYEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVMQSDIFKEELEQMYPVVEDGGSDSAAFDNVLELLTINGVLSLPEAVMLMVPEAWQGNQHMDPKKAAFYEWAACQMEPWDGPALFTFADGRYCGANLDRNGLRPCRFYVMDDDRIICASEVGTIPVEPETVIQKGRLQPGRMLLVDTQAGRIIDDKELKEAVSSRYDFRAWLDSELITLPKVVEIMEQALDLAPKLDDKAIQADPLLLSYGYTHEQVSLLLAPMAADEKEALGSMGNDAPLACLTQAPRLLYDYFRQLFAQVTNPPIDPIRESIVMSLECYVGPQGNLLEMDASQCGRLLLPSPILSIEEFNAVKNMSNKYSEWTVKTIDLTFPKNQGIQGYIKHLDEICNEASAAIESRDRVIVLSDRNTSADRVPVSAVLASAMVHHHLVSNKWRSMVALVVETAEAREVHHMCVLLGYGADAINPYLAMECILKLNREGLIKKKTTNETLIRNYKHACDGGILKVMSKMGISTLASYKGAQIFEILGLDETVVERCFRGTASRIQGMTFELPIAEEAFRFHERGFPTRETILPSGLPESGEYHWRDGGEPHVNDPTSIANIQDAVRTKNDKSYEAYSRSEYEQIKNCTLRGLLDFKFEDCTPVPIDQVEPWTDIVRRFCTGAMSYGSISMESHSTLAVAMNRLGGKSNTGEGGEDPERSQRMPNGDTMRSAIKQVASGRFGVTSAYLADSDELQIKMAQGAKPGEGGELPGHKVSKSIARTRHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCSSPRSRVSVKLVSEVGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVVVQTDGQLKTGRDVALACLLGAEEWGFATAPLIAMGCVFMRKCHLNTCPVGIATQDPEVRKKFTGTPEHVINFFYYVANELRAIMAQLGFRTINEMVGHVEVLKMRDDLRTHKTANIDLSLLLTPAHKLRPGVATFNVRKQDHKLHVRLDNKLISESELTLDKGLPSRIECDIVNTDRAMGTSLSYHISKRYGEAGLPMDTVHVNIKGSAGQSFGAFLAPGVTLELEGDANDYVGKGLSGGRLIVYPPRSAVFQSEENILIGNTCLYGATTGTCFFRGVAAERFAVRNSGATAVVEGVGDHGCEYMTGGRVVVLGSTGRNFAAGMSGGIAYISDVHGDFHSKLNGEMVETSDFEDPAEIAFVRGLIEDHHHYTGSERAARILVDFNRALPRFIKILPVDYKRVLEEEAAKAAEAKRAEYNLPAVSGVQHKKSEKVAKLQDLEEAVGDNAAEKKRALVLDKTRGFKMYKRRQEKYRPVNSRLKDWAELSSRLDEDELKYQSARCMDCGVPFCQSETGCPISNIIPKWNELVFQNQWKDALNRLLMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSIECAIIDRGFEMGWMVPQPPKVRTGKTVAIIGSGPAGLAAADQLNRAGHLVTVYERADRLGGLLMYGIPNMKLDKRIVKRRTDFMASEGIIFKTGVAVGEEGHPSLNDLRASNSAVVIATGATVARDLPIKGRQLDGIHYAMEFLHKNTKSLLDSELADNTYISAKGKDVVVIGGGDTGNDCIGTSLRHGAKSVTNFELLPQPPPERANDNPWPQWPRIYRVDYGHTEVRQHTGKDPREYCIMSEEFMDDGSGKVKGINTIRVEWTKSPSGGWDMKKVEGSQQFFPADLVLLAMGFLGPEARVLGDEIEKDARKNVKTAPGKYSTNLEGVFAAGDARRGQSLIVWGINEGRQAAREIDLYLEKYTNLPVTGGITKRTAQEIFSQIKVEA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM056054
EMBL· GenBank· DDBJ
CAJ20840.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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