Q497H5 · Q497H5_MOUSE
- ProteinFat1 protein
- GeneFat1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1309 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | cell junction | |
Cellular Component | cytosol | |
Cellular Component | filopodium | |
Cellular Component | lamellipodium | |
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Biological Process | actin filament organization | |
Biological Process | camera-type eye development | |
Biological Process | camera-type eye morphogenesis | |
Biological Process | cell-cell adhesion | |
Biological Process | epithelial cell morphogenesis | |
Biological Process | establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis | |
Biological Process | establishment or maintenance of cell polarity | |
Biological Process | establishment or maintenance of epithelial cell apical/basal polarity | |
Biological Process | generation of neurons | |
Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules | |
Biological Process | lens development in camera-type eye | |
Biological Process | positive regulation of vascular associated smooth muscle cell migration |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ497H5
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 892-912 | Helical | ||||
Sequence: GIGIIVFIAGIVLLVMVFVLC |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 509↔526 | |||||
Sequence: CPAGSECVADPREEKYSC | ||||||
Disulfide bond | 750↔759 | |||||
Sequence: CSALYVGTFC | ||||||
Disulfide bond | 788↔797 | |||||
Sequence: CRGLYTGQRC | ||||||
Disulfide bond | 825↔834 | |||||
Sequence: CDSGFRGERC | ||||||
Disulfide bond | 863↔872 | |||||
Sequence: CSQEYRGKHC |
Keywords
- PTM
Proteomic databases
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-45 | Cadherin | ||||
Sequence: LDYKSSHEYYLTVEATDGGTPSLSDVATVNINVTDINDNSPVF | ||||||
Domain | 46-150 | Cadherin | ||||
Sequence: SQDTYTTVVSEDAALEQPVITIMADDADGPSNSHIHYSIIEGNQGSPFTIDPVRGEVKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLF | ||||||
Domain | 151-255 | Cadherin | ||||
Sequence: SRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFFFTIVSGNDENAFEVNQHGVLLTAATIKRKVKDHYLLHVKVADSGKPQLSSMTHIDIRVIEESIHPPAI | ||||||
Domain | 271-357 | Cadherin | ||||
Sequence: GGVIGKIHATDQDVYDTLMYSLDPHMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTVAIRF | ||||||
Domain | 500-537 | EGF-like | ||||
Sequence: VHHGCEDNPCPAGSECVADPREEKYSCVCPGGGFGKCP | ||||||
Domain | 539-719 | Laminin G | ||||
Sequence: SSSITFTGNSFVKYRLLENENRLEMKLSMRLRTYSSHAVVMYARGTDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVFFGGHLRQQGTKHGRGAQVASGFRGCMDSIYLNGQELPLNNKPRAYAHIEEWVDLSHGC | ||||||
Domain | 723-760 | EGF-like | ||||
Sequence: ATEDCSSSPCQNGGVCNPSPTGGYYCKCSALYVGTFCE | ||||||
Domain | 762-798 | EGF-like | ||||
Sequence: SVNPCSSNPCLYGGTCMVDNGGFVCQCRGLYTGQRCQ | ||||||
Domain | 799-835 | EGF-like | ||||
Sequence: LSPYCKDDPCKNGGTCFDSLDGAVCQCDSGFRGERCQ | ||||||
Domain | 837-873 | EGF-like | ||||
Sequence: DIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCE | ||||||
Region | 964-1000 | Disordered | ||||
Sequence: ISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPE | ||||||
Compositional bias | 965-983 | Polar residues | ||||
Sequence: SYTPSIPSDSRNNLDRNSF | ||||||
Region | 1013-1037 | Disordered | ||||
Sequence: SVAPNLPPPPPSNSPSDSDSIQKPS | ||||||
Region | 1054-1107 | Disordered | ||||
Sequence: SKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNESLAAPDLSKPRGYHWDT | ||||||
Compositional bias | 1066-1089 | Polar residues | ||||
Sequence: YSARESLSEVQSLSSFQSESCDDN | ||||||
Region | 1131-1201 | Disordered | ||||
Sequence: HTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLPPEFSDQFESIHPPRDMPAAGSLGSSSR | ||||||
Compositional bias | 1154-1174 | Pro residues | ||||
Sequence: ESDFPPPPEDFPAPDELPPLP | ||||||
Region | 1220-1245 | Disordered | ||||
Sequence: MSEPQKQGAGENSPCREPYTPYPPGY | ||||||
Region | 1285-1309 | Disordered | ||||
Sequence: YESGDDGHFEEVTIPPLDSQQHTEV |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length1,309
- Mass (Da)143,805
- Last updated2005-09-13 v1
- Checksum9A208181C4136D09
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: E | ||||||
Compositional bias | 965-983 | Polar residues | ||||
Sequence: SYTPSIPSDSRNNLDRNSF | ||||||
Compositional bias | 1066-1089 | Polar residues | ||||
Sequence: YSARESLSEVQSLSSFQSESCDDN | ||||||
Compositional bias | 1154-1174 | Pro residues | ||||
Sequence: ESDFPPPPEDFPAPDELPPLP |