Q49744 · RNZ_MYCLE
- ProteinPutative ribonuclease Z
- Genernz
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids220 (go to sequence)
- Protein existenceUncertain
- Annotation score3/5
Function
function
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
Catalytic activity
Cofactor
Note: Binds 2 Zn2+ ions.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 38 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 40 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 42 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 42 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: D | ||||||
Binding site | 130 | Zn2+ 1 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Binding site | 215 | Zn2+ 2 (UniProtKB | ChEBI); catalytic | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3'-tRNA processing endoribonuclease activity | |
Molecular Function | metal ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative ribonuclease Z
- EC number
- Short namesRNase Z; tRNase Z
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionQ49744
- Secondary accessions
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000155877 | 1-220 | Putative ribonuclease Z | |||
Sequence: MQAGRQLFLVDCWLGVLQRASAGPTHTPAVCQRCCSTHLHGDRISDLGDLLITHWVTTFALDPPPLPIIGSPDTAETVEAKLKASGHDIEYQITHHTYLNTPPLIEVYEYTKGFVGAPPDGVSIRGSTNHGPVTPTIGFRIESGPTSVVLTGGTVPCASLDELAAEADALVHTIIRKNIVIRVHQQADQGHLQPPLVNRASDSNRGARGHRHPGHNVLCP |
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length220
- Mass (Da)23,634
- Last updated2004-01-16 v2
- ChecksumC3F0F9B5B2F3F92A
Sequence caution
Keywords
- Technical term