Q48EI5 · CH60_PSE14
- ProteinChaperonin GroEL
- GenegroEL
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids547 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 30-33 | ATP (UniProtKB | ChEBI) | |||
Binding site | 51 | ATP (UniProtKB | ChEBI) | |||
Binding site | 87-91 | ATP (UniProtKB | ChEBI) | |||
Binding site | 415 | ATP (UniProtKB | ChEBI) | |||
Binding site | 479-481 | ATP (UniProtKB | ChEBI) | |||
Binding site | 495 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | GroEL-GroES complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent protein folding chaperone | |
Molecular Function | isomerase activity | |
Molecular Function | unfolded protein binding | |
Biological Process | chaperone cofactor-dependent protein refolding | |
Biological Process | protein refolding | |
Biological Process | response to heat |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChaperonin GroEL
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ48EI5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000256952 | 1-547 | Chaperonin GroEL | ||
Interaction
Subunit
Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
Structure
Sequence
- Sequence statusComplete
- Length547
- Mass (Da)57,196
- Last updated2005-09-13 v1
- MD5 Checksum3F90F23639C99BD8EF3F68B550AF09C0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000058 EMBL· GenBank· DDBJ | AAZ36265.1 EMBL· GenBank· DDBJ | Genomic DNA |