Q47422 · GSPM_DICCH

Function

function

Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Plays a role in the complex assembly and recruits OutL resulting in a stable complex in the inner membrane (By similarity).
Provides thus a link between the energy-providing OutE protein in the cytoplasm and the rest of the T2SS machinery (PubMed:11266368).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componenttype II protein secretion system complex
Biological Processprotein secretion by the type II secretion system

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Type II secretion system protein M
  • Short names
    T2SS protein M
  • Alternative names
    • General secretion pathway protein M
    • Pectic enzymes secretion protein OutM

Gene names

    • Name
      outM

Organism names

Accessions

  • Primary accession
    Q47422

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-16Cytoplasmic
Transmembrane17-37Helical
Topological domain38-161Periplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002073251-161Type II secretion system protein M

Interaction

Subunit

Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus (By similarity).
Forms homodimers (By similarity).
Interacts with OutL/GspL (PubMed:11266368).
Interacts with OutE/GspE and OutF/GspF (By similarity).

Family & Domains

Sequence similarities

Belongs to the GSP M family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    161
  • Mass (Da)
    18,622
  • Last updated
    1996-11-01 v1
  • Checksum
    DDEDD3C69345D920
MNELRRRWQVMSQRERLMALACGGLVVLCLLYYLIWAPWQESVRQWQMTVERERQTVRWMQQQPPRFRRRKVRGGRXPVAISANGIGAQSAVRYGITVLRMQPQESQVSVTLARSDFNNLLHWLAELEQKNGVITQGIDVTAVPNSPGIVEVTRLSLERVL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
L02214
EMBL· GenBank· DDBJ
AAA24840.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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