Q47142 · HCAT_ECOLI
- ProteinProbable 3-phenylpropionic acid transporter
- GenehcaT
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids379 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Probable permease involved in the uptake of 3-phenylpropionic acid.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | lactose binding | |
Molecular Function | lactose:proton symporter activity |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProbable 3-phenylpropionic acid transporter
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ47142
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-4 | Cytoplasmic | ||||
Sequence: MVLQ | ||||||
Transmembrane | 5-31 | Helical; Name=1 | ||||
Sequence: STRWLALGYFTYFFSYGIFLPFWSVWL | ||||||
Topological domain | 32-37 | Periplasmic | ||||
Sequence: KGIGLT | ||||||
Transmembrane | 38-66 | Helical; Name=2 | ||||
Sequence: PETIGLLLGAGLVARFLGSLLIAPRVSDP | ||||||
Topological domain | 67-70 | Cytoplasmic | ||||
Sequence: SRLI | ||||||
Transmembrane | 71-96 | Helical; Name=3 | ||||
Sequence: SALRVLALLTLLFAVAFWAGAHVAWL | ||||||
Topological domain | 97-100 | Periplasmic | ||||
Sequence: MLVM | ||||||
Transmembrane | 101-118 | Helical; Name=4 | ||||
Sequence: IGFNLFFSPLVPLTDALA | ||||||
Topological domain | 119-129 | Cytoplasmic | ||||
Sequence: NTWQKQFPLDY | ||||||
Transmembrane | 130-152 | Helical; Name=5 | ||||
Sequence: GKVRLWGSVAFVIGSALTGKLVT | ||||||
Topological domain | 153-155 | Periplasmic | ||||
Sequence: MFD | ||||||
Transmembrane | 156-175 | Helical; Name=6 | ||||
Sequence: YRVILALLTLGVASMLLGFL | ||||||
Topological domain | 176-207 | Cytoplasmic | ||||
Sequence: IRPTIQPQGASRQQESTGWSAWLALVRQNWRF | ||||||
Transmembrane | 208-227 | Helical; Name=7 | ||||
Sequence: LACVCLLQGAHAAYYGFSAI | ||||||
Topological domain | 228-231 | Periplasmic | ||||
Sequence: YWQA | ||||||
Transmembrane | 232-256 | Helical; Name=8 | ||||
Sequence: AGYSASAVGYLWSLGVVAEVIIFAL | ||||||
Topological domain | 257-266 | Cytoplasmic | ||||
Sequence: SNKLFRRCSA | ||||||
Transmembrane | 267-286 | Helical; Name=9 | ||||
Sequence: RDMLLISAICGVVRWGIMGA | ||||||
Topological domain | 287-289 | Periplasmic | ||||
Sequence: TTA | ||||||
Transmembrane | 290-312 | Helical; Name=10 | ||||
Sequence: LPWLIVVQILHCGTFTVCHLAAM | ||||||
Topological domain | 313-323 | Cytoplasmic | ||||
Sequence: RYIAARQGSEV | ||||||
Transmembrane | 324-351 | Helical; Name=11 | ||||
Sequence: IRLQAVYSAVAMGGSIAIMTVFAGFLYQ | ||||||
Topological domain | 352-354 | Periplasmic | ||||
Sequence: YLG | ||||||
Transmembrane | 355-375 | Helical; Name=12 | ||||
Sequence: HGVFWVMALVALPAMFLRPKV | ||||||
Topological domain | 376-379 | Cytoplasmic | ||||
Sequence: VPSC |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000196189 | 1-379 | Probable 3-phenylpropionic acid transporter | |||
Sequence: MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLLLGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIGFNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVILALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAHAAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAICGVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC |
Proteomic databases
Structure
Sequence
- Sequence statusComplete
- Length379
- Mass (Da)41,593
- Last updated1997-11-01 v2
- Checksum76429AD807623482
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 191 | in Ref. 2; CAA71954 | ||||
Sequence: S → N |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Z37966 EMBL· GenBank· DDBJ | CAA86021.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift | |
Y11071 EMBL· GenBank· DDBJ | CAA71954.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
U00096 EMBL· GenBank· DDBJ | AAC75589.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP009048 EMBL· GenBank· DDBJ | BAA16431.1 EMBL· GenBank· DDBJ | Genomic DNA |