Q43133 · GGPPS_SINAL

Function

function

Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 Mg2+ ions per subunit.

Pathway

Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site112isopentenyl diphosphate (UniProtKB | ChEBI)
Binding site115isopentenyl diphosphate (UniProtKB | ChEBI)
Binding site144isopentenyl diphosphate (UniProtKB | ChEBI)
Binding site151Mg2+ 1 (UniProtKB | ChEBI)
Binding site151Mg2+ 2 (UniProtKB | ChEBI)
Binding site157Mg2+ 1 (UniProtKB | ChEBI)
Binding site157Mg2+ 2 (UniProtKB | ChEBI)
Binding site162dimethylallyl diphosphate (UniProtKB | ChEBI)
Binding site163isopentenyl diphosphate (UniProtKB | ChEBI)
Binding site251dimethylallyl diphosphate (UniProtKB | ChEBI)
Binding site252dimethylallyl diphosphate (UniProtKB | ChEBI)
Binding site289dimethylallyl diphosphate (UniProtKB | ChEBI)
Binding site306dimethylallyl diphosphate (UniProtKB | ChEBI)
Binding site316dimethylallyl diphosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast stroma
Cellular Componentchromoplast
Molecular Functiondimethylallyltranstransferase activity
Molecular Functionfarnesyltranstransferase activity
Molecular Functiongeranyltranstransferase activity
Molecular Functionmetal ion binding
Biological Processcarotenoid biosynthetic process
Biological Processfarnesyl diphosphate biosynthetic process
Biological Processgeranyl diphosphate biosynthetic process
Biological Processgeranylgeranyl diphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic
  • EC number
  • Short names
    GGPP synthase; GGPS
  • Alternative names
    • (2E,6E)-farnesyl diphosphate synthase
    • Dimethylallyltranstransferase (EC:2.5.1.1) . EC:2.5.1.1 (UniProtKB | ENZYME | Rhea)
    • Farnesyl diphosphate synthase
    • Farnesyltranstransferase (EC:2.5.1.29) . EC:2.5.1.29 (UniProtKB | ENZYME | Rhea)
    • Geranyltranstransferase (EC:2.5.1.10) . EC:2.5.1.10 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      GGPS1
    • Synonyms
      GGPS

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Brassiceae > Sinapis

Accessions

  • Primary accession
    Q43133

Subcellular Location

PTM/Processing

Features

Showing features for chain, transit peptide.

Type
IDPosition(s)Description
ChainPRO_0000016474?-366Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic
Transit peptide1-?Chloroplast and chromoplast

Interaction

Subunit

Dimer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region44-65Disordered

Sequence similarities

Belongs to the FPP/GGPP synthase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    366
  • Mass (Da)
    39,432
  • Last updated
    1996-11-01 v1
  • Checksum
    1EADBFD9C4CF4F77
MASSVTPLGSWVLLHHHPSTILTQSRSRSPPSLITLKPISLTPKRTVSSSSSSSLITKEDNNLKSSSSSFDFMSYIIRKADSVNKALDSAVPLREPLKIHEAMRYSLLAGGKRVRPVLCIAACELVGGEESLAMPARCAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVYGEDVAVLAGDALLSFAFEHLASATSSEVSPARVVRAVGELAKAIGTEGLVAGQVVDISSEGLDLNNVGLEHLKFIHLHKTAALLEASAVLGGIIGGGSDEEIERLRKFARCIGLLFQVVDDILDVTKSSQELGKTAGKDLIADKLTYPKLMGLEKSREFAEKLNTEARDQLLGFDSDKVAPLLALANYIANRQN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X98795
EMBL· GenBank· DDBJ
CAA67330.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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