Q43133 · GGPPS_SINAL
- ProteinGeranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic
- GeneGGPS1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids366 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
Catalytic activity
- isopentenyl diphosphate + dimethylallyl diphosphate = (2E)-geranyl diphosphate + diphosphate
Cofactor
Note: Binds 2 Mg2+ ions per subunit.
Pathway
Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 112 | isopentenyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 115 | isopentenyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 144 | isopentenyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 151 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 151 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 157 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 157 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 162 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 163 | isopentenyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 251 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 252 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 289 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 306 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
Binding site | 316 | dimethylallyl diphosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast stroma | |
Cellular Component | chromoplast | |
Molecular Function | dimethylallyltranstransferase activity | |
Molecular Function | farnesyltranstransferase activity | |
Molecular Function | geranyltranstransferase activity | |
Molecular Function | metal ion binding | |
Biological Process | carotenoid biosynthetic process | |
Biological Process | farnesyl diphosphate biosynthetic process | |
Biological Process | geranyl diphosphate biosynthetic process | |
Biological Process | geranylgeranyl diphosphate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGeranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic
- EC number
- Short namesGGPP synthase; GGPS
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Brassiceae > Sinapis
Accessions
- Primary accessionQ43133
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000016474 | ?-366 | Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic | ||
Transit peptide | 1-? | Chloroplast and chromoplast | |||
Interaction
Subunit
Dimer.
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length366
- Mass (Da)39,432
- Last updated1996-11-01 v1
- Checksum1EADBFD9C4CF4F77
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X98795 EMBL· GenBank· DDBJ | CAA67330.1 EMBL· GenBank· DDBJ | mRNA |