Q43128 · PMA10_ARATH
- ProteinATPase 10, plasma membrane-type
- GeneAHA10
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids947 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
The plasma membrane H+ ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.
Catalytic activity
- ATP + H+(in) + H2O = ADP + 2 H+(out) + phosphate
CHEBI:30616 + H+ (in)CHEBI:15378+ CHEBI:15377 = CHEBI:456216 + 2 H+ (out)CHEBI:15378+ CHEBI:43474
Features
Showing features for active site, binding site.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | plant-type vacuole membrane | |
Cellular Component | plasmodesma | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATPase-coupled monoatomic cation transmembrane transporter activity | |
Molecular Function | metal ion binding | |
Molecular Function | P-type ion transporter activity | |
Molecular Function | P-type proton-exporting transporter activity | |
Biological Process | proanthocyanidin biosynthetic process | |
Biological Process | proton export across plasma membrane | |
Biological Process | seed coat development | |
Biological Process | vacuolar acidification | |
Biological Process | vacuole organization |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATPase 10, plasma membrane-type
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ43128
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-69 | Cytoplasmic | ||||
Sequence: MAEDLDKPLLDPDTFNRKGIDLGILPLEEVFEYLRTSPQGLLSGDAEERLKIFGPNRLEEKQENRFVKF | ||||||
Transmembrane | 70-89 | Helical; Name=1 | ||||
Sequence: LGFMWNPLSWVMEAAALMAI | ||||||
Topological domain | 90-101 | Extracellular | ||||
Sequence: ALANSQSLGPDW | ||||||
Transmembrane | 102-122 | Helical; Name=2 | ||||
Sequence: EDFTGIVCLLLINATISFFEE | ||||||
Topological domain | 123-251 | Cytoplasmic | ||||
Sequence: NNAGNAAAALMARLALKTRVLRDGQWQEQDASILVPGDIISIKLGDIIPADARLLEGDPLKIDQSVLTGESLPVTKKKGEQVFSGSTCKQGEIEAVVIATGSTTFFGKTARLVDSTDVTGHFQQVLTSI | ||||||
Transmembrane | 252-272 | Helical; Name=3 | ||||
Sequence: GNFCICSIAVGMVLEIIIMFP | ||||||
Topological domain | 273-281 | Extracellular | ||||
Sequence: VQHRSYRIG | ||||||
Transmembrane | 282-299 | Helical; Name=4 | ||||
Sequence: INNLLVLLIGGIPIAMPT | ||||||
Topological domain | 300-650 | Cytoplasmic | ||||
Sequence: VLSVTLAIGSHRLSQQGAITKRMTAIEEMAGMDVLCCDKTGTLTLNSLTVDKNLIEVFVDYMDKDTILLLAGRASRLENQDAIDAAIVSMLADPREARANIREIHFLPFNPVDKRTAITYIDSDGKWYRATKGAPEQVLNLCQQKNEIAQRVYAIIDRFAEKGLRSLAVAYQEIPEKSNNSPGGPWRFCGLLPLFDPPRHDSGETILRALSLGVCVKMITGDQLAIAKETGRRLGMGTNMYPSSSLLGHNNDEHEAIPVDELIEMADGFAGVFPEHKYEIVKILQEMKHVVGMTGDGVNDAPALKKADIGIAVADATDAARSSADIVLTDPGLSVIISAVLTSRAIFQRMR | ||||||
Transmembrane | 651-672 | Helical; Name=5 | ||||
Sequence: NYTVYAVSITIRIVLGFTLLAL | ||||||
Topological domain | 673-677 | Extracellular | ||||
Sequence: IWEYD | ||||||
Transmembrane | 678-700 | Helical; Name=6 | ||||
Sequence: FPPFMVLIIAILNDGTIMTISKD | ||||||
Topological domain | 701-716 | Cytoplasmic | ||||
Sequence: RVRPSPTPESWKLNQI | ||||||
Transmembrane | 717-737 | Helical; Name=7 | ||||
Sequence: FATGIVIGTYLALVTVLFYWI | ||||||
Topological domain | 738-758 | Extracellular | ||||
Sequence: IVSTTFFEKHFHVKSIANNSE | ||||||
Transmembrane | 759-779 | Helical; Name=8 | ||||
Sequence: QVSSAMYLQVSIISQALIFVT | ||||||
Topological domain | 780-791 | Cytoplasmic | ||||
Sequence: RSRGWSFFERPG | ||||||
Transmembrane | 792-812 | Helical; Name=9 | ||||
Sequence: TLLIFAFILAQLAATLIAVYA | ||||||
Topological domain | 813-820 | Extracellular | ||||
Sequence: NISFAKIT | ||||||
Transmembrane | 821-841 | Helical; Name=10 | ||||
Sequence: GIGWRWAGVIWLYSLIFYIPL | ||||||
Topological domain | 842-947 | Cytoplasmic | ||||
Sequence: DVIKFVFHYALSGEAWNLVLDRKTAFTYKKDYGKDDGSPNVTISQRSRSAEELRGSRSRASWIAEQTRRRAEIARLLEVHSVSRHLESVIKLKQIDQRMIRAAHTV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000046283 | 1-947 | ATPase 10, plasma membrane-type | |||
Sequence: MAEDLDKPLLDPDTFNRKGIDLGILPLEEVFEYLRTSPQGLLSGDAEERLKIFGPNRLEEKQENRFVKFLGFMWNPLSWVMEAAALMAIALANSQSLGPDWEDFTGIVCLLLINATISFFEENNAGNAAAALMARLALKTRVLRDGQWQEQDASILVPGDIISIKLGDIIPADARLLEGDPLKIDQSVLTGESLPVTKKKGEQVFSGSTCKQGEIEAVVIATGSTTFFGKTARLVDSTDVTGHFQQVLTSIGNFCICSIAVGMVLEIIIMFPVQHRSYRIGINNLLVLLIGGIPIAMPTVLSVTLAIGSHRLSQQGAITKRMTAIEEMAGMDVLCCDKTGTLTLNSLTVDKNLIEVFVDYMDKDTILLLAGRASRLENQDAIDAAIVSMLADPREARANIREIHFLPFNPVDKRTAITYIDSDGKWYRATKGAPEQVLNLCQQKNEIAQRVYAIIDRFAEKGLRSLAVAYQEIPEKSNNSPGGPWRFCGLLPLFDPPRHDSGETILRALSLGVCVKMITGDQLAIAKETGRRLGMGTNMYPSSSLLGHNNDEHEAIPVDELIEMADGFAGVFPEHKYEIVKILQEMKHVVGMTGDGVNDAPALKKADIGIAVADATDAARSSADIVLTDPGLSVIISAVLTSRAIFQRMRNYTVYAVSITIRIVLGFTLLALIWEYDFPPFMVLIIAILNDGTIMTISKDRVRPSPTPESWKLNQIFATGIVIGTYLALVTVLFYWIIVSTTFFEKHFHVKSIANNSEQVSSAMYLQVSIISQALIFVTRSRGWSFFERPGTLLIFAFILAQLAATLIAVYANISFAKITGIGWRWAGVIWLYSLIFYIPLDVIKFVFHYALSGEAWNLVLDRKTAFTYKKDYGKDDGSPNVTISQRSRSAEELRGSRSRASWIAEQTRRRAEIARLLEVHSVSRHLESVIKLKQIDQRMIRAAHTV | ||||||
Modified residue | 897 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 929 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 946 | Phosphothreonine | ||||
Sequence: T |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Found primarily in developing seeds. Expressed in guard cells, mesophyll cells, leaves and roots (PubMed:15821287).
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length947
- Mass (Da)104,815
- Last updated2001-01-24 v2
- Checksum1E951DFCC0DA5C24
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
S74033 EMBL· GenBank· DDBJ | AAB32310.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
AC007651 EMBL· GenBank· DDBJ | AAD50009.3 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE29565.1 EMBL· GenBank· DDBJ | Genomic DNA |