Q42381 · HLS1_ARATH

Function

function

Ethylene-responsive N-acetyltransferase required for differential cell elongation in the hypocotyl. Regulates apical hook formation of dark-grown seedlings. May control differential cell growth by regulating auxin activity. May be involved in negative feedback regulation of auxin homeostasis through the control of GH3-like genes. Modulates de novo shoot organogenesis.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionN-acetyltransferase activity
Biological Processauxin-activated signaling pathway
Biological Processphotomorphogenesis
Biological Processresponse to ethylene
Biological Processunidimensional cell growth

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable N-acetyltransferase HLS1
  • EC number
  • Alternative names
    • Protein CONSTITUTIVE PHOTOMORPHOGENIC 3
    • Protein HOOKLESS 1
    • Protein UNUSUAL SUGAR RESPONSE 2

Gene names

    • Name
      HLS1
    • Synonyms
      COP3, UNS2
    • ORF names
      F19F18.70
    • Ordered locus names
      At4g37580

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q42381

Proteomes

Organism-specific databases

Genome annotation databases

Phenotypes & Variants

Disruption phenotype

Unable to develop apical hook in the dark. Reduced length of dark-grown hypocotyls and reduced leaf initiation rate in light-grown seedlings.

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis327In hls1-6; strong allele.
Mutagenesis346In hls1-1 and hls4-1; strong allele.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 30 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004234031-403Probable N-acetyltransferase HLS1

Proteomic databases

Expression

Induction

By ethylene.

Gene expression databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q42381CAF1-6 Q9SAI24EBI-15207218, EBI-4465274

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-177N-acetyltransferase

Sequence similarities

Belongs to the acetyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    403
  • Mass (Da)
    44,934
  • Last updated
    1996-11-01 v1
  • Checksum
    E2A9DD0C2FA2DFE8
MTVVREYDPTRDLVGVEDVERRCEVGPSGKLSLFTDLLGDPICRIRHSPSYLMLVAEMGTEKKEIVGMIRGCIKTVTCGQKLDLNHKSQNDVVKPLYTKLAYVLGLRVSPFHRRQGIGFKLVKMMEEWFRQNGAEYSYIATENDNQASVNLFTGKCGYSEFRTPSILVNPVYAHRVNVSRRVTVIKLEPVDAETLYRIRFSTTEFFPRDIDSVLNNKLSLGTFVAVPRGSCYGSGSGSWPGSAKFLEYPPESWAVLSVWNCKDSFLLEVRGASRLRRVVAKTTRVVDKTLPFLKLPSIPSVFEPFGLHFMYGIGGEGPRAVKMVKSLCAHAHNLAKAGGCGVVAAEVAGEDPLRRGIPHWKVLSCDEDLWCIKRLGDDYSDGVVGDWTKSPPGVSIFVDPREF

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B3D5A0A1P8B3D5_ARATHHLS1346

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U50399
EMBL· GenBank· DDBJ
AAB03773.1
EMBL· GenBank· DDBJ
mRNA
U50400
EMBL· GenBank· DDBJ
AAB03774.1
EMBL· GenBank· DDBJ
Genomic DNA
AL035605
EMBL· GenBank· DDBJ
CAB38297.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161591
EMBL· GenBank· DDBJ
CAB80423.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE86813.1
EMBL· GenBank· DDBJ
Genomic DNA
AK175660
EMBL· GenBank· DDBJ
BAD43423.1
EMBL· GenBank· DDBJ
mRNA
AK176117
EMBL· GenBank· DDBJ
BAD43880.1
EMBL· GenBank· DDBJ
mRNA
BT026435
EMBL· GenBank· DDBJ
ABH04542.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp