Q3ZCJ6 · Q3ZCJ6_BOVIN

  • Protein
    Epoxide hydrolase
  • Gene
    EPHX1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site226Nucleophile
Active site373Proton donor
Active site427Proton acceptor

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functioncis-stilbene-oxide hydrolase activity
Molecular Functionepoxide hydrolase activity
Biological Processarachidonic acid metabolic process
Biological Processcatabolic process
Biological Processepoxide metabolic process
Biological Processresponse to toxic substance

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Epoxide hydrolase
  • EC number

Gene names

    • Name
      EPHX1

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Crossbred x Angus
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q3ZCJ6

Proteomes

Organism-specific databases

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass type III membrane protein
Membrane
; Single-pass type III membrane protein
Microsome membrane
; Single-pass type III membrane protein

Keywords

PTM/Processing

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-157Epoxide hydrolase N-terminal

Sequence similarities

Belongs to the peptidase S33 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    451
  • Mass (Da)
    52,197
  • Last updated
    2005-09-27 v1
  • Checksum
    805FB6B956A4FAB6
MWLEILLASVLGFVIYWFVSKDKEETLPLEDGWWGPGVRPTAGEDKSIRPFKVETSDEEINDLHQRIDRVRLTPPLEDSRFHYGFNSNYLKKIISYWRNEFDWRKQVEILNKYPHFKTKIEGLDIHFIHVKPPNLPSGQTPKPLLMVHGWPGSFYEFYKIIPFLTDPKNHGLSDEHVFEVICPSIPGYSFSEASSKKGFNSVATARIFYKLMLRLGFQKFYIQGGDWGALICTNMAQLVPSHIKGLHLNMALILRNFYTLTLPLGRCFGGLFGYTERDMELIYPFKKIFFSLLRESGYLHIQSTKPDTVGCALNDSPVGLAAYILEKFSTWTNSEFRDLEDGGLERKFSLDDLLTGIMLYWTTGTITSSQRFYKENLGQVNKHEMLKVYVPTGFAAFPCELMHLPEKWVKTKYPNLISYSYMPRGGHFAAFEEPELLAQDIRKFVGLQERQ

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3Q1M9R4A0A3Q1M9R4_BOVINEPHX1510
F6RAL2F6RAL2_BOVINEPHX1412

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC102117
EMBL· GenBank· DDBJ
AAI02118.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp