Q3UVN4 · Q3UVN4_MOUSE
- ProteinDelta-like protein
- GeneJag1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1218 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Putative Notch ligand involved in the mediation of Notch signaling.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | molecular adaptor activity | |
Molecular Function | Notch binding | |
Molecular Function | phospholipid binding | |
Biological Process | negative regulation of cell migration | |
Biological Process | negative regulation of cell-cell adhesion | |
Biological Process | negative regulation of cell-matrix adhesion | |
Biological Process | negative regulation of stem cell differentiation | |
Biological Process | neuronal stem cell population maintenance | |
Biological Process | Notch signaling pathway | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | pulmonary artery morphogenesis | |
Biological Process | pulmonary valve morphogenesis | |
Biological Process | T cell mediated immunity |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameDelta-like protein
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ3UVN4
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1068-1093 | Helical | ||||
Sequence: FLVPLLSSVLTVAWVCCLVTAFYWCV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-30 | |||||
Sequence: MRSPRTRGRPGRPLSLLLALLCALRAKVCG | ||||||
Chain | PRO_5014309232 | 31-1218 | Delta-like protein | |||
Sequence: ASGQFELEILSMQNVNGELQNGNCCGGVRNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTIQPDSIIEKASHSGMINPSRQWQTLKQNTGIAHFEYQIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDCNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNARSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCKNGGTCIDGVNSYKCICSDGWEGAHCENNINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICTQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYQCICPPGHSGAKCHEVSGRSCITMGRVILDGAKWDDDCNTCQCLNGRVACSKVWCGPRPCRLHKSHNECPSGQSCIPVLDDQCFVRPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSLSANNEIHVAISAEDIRDDGNPVKEITDKIIDLVSKRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVAWVCCLVTAFYWCVRKRRKPSSHTHSAPEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKVRFAKQPVYTLVDREEKAPSGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV | ||||||
Disulfide bond | 187↔196 | |||||
Sequence: CDDHYYGFGC | ||||||
Disulfide bond | 200↔212 | |||||
Sequence: CRPRDDFFGHYAC | ||||||
Disulfide bond | 220↔229 | |||||
Sequence: CMEGWMGPDC | ||||||
Disulfide bond | 253↔262 | |||||
Sequence: CQYGWQGLYC | ||||||
Disulfide bond | 324↔333 | |||||
Sequence: CPEGYSGPNC | ||||||
Disulfide bond | 362↔371 | |||||
Sequence: CSPGWTGPTC | ||||||
Disulfide bond | 400↔409 | |||||
Sequence: CPPQWTGKTC | ||||||
Disulfide bond | 438↔447 | |||||
Sequence: CLPGWMGQNC | ||||||
Disulfide bond | 454↔464 | |||||
Sequence: CLGQCQNDASC | ||||||
Disulfide bond | 475↔484 | |||||
Sequence: CPPGYAGDHC | ||||||
Disulfide bond | 513↔522 | |||||
Sequence: CPTGFSGNLC | ||||||
Disulfide bond | 551↔560 | |||||
Sequence: CPEDYEGKNC | ||||||
Disulfide bond | 617↔626 | |||||
Sequence: CNKGFTGTYC | ||||||
Disulfide bond | 655↔664 | |||||
Sequence: CSDGWEGAHC | ||||||
Disulfide bond | 693↔702 | |||||
Sequence: CKNGWKGKTC | ||||||
Disulfide bond | 731↔740 | |||||
Sequence: CPGGWEGTTC | ||||||
Disulfide bond | 770↔779 | |||||
Sequence: CKEGWEGPIC | ||||||
Disulfide bond | 808↔817 | |||||
Sequence: CAPGFAGPDC | ||||||
Disulfide bond | 846↔855 | |||||
Sequence: CPPGHSGAKC |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 185-229 | DSL | ||||
Sequence: VTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPDC | ||||||
Domain | 230-263 | EGF-like | ||||
Sequence: NKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCD | ||||||
Domain | 296-334 | EGF-like | ||||
Sequence: DLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCE | ||||||
Domain | 336-372 | EGF-like | ||||
Sequence: AEHACLSDPCHNRGSCKETSSGFECECSPGWTGPTCS | ||||||
Domain | 374-410 | EGF-like | ||||
Sequence: NIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ | ||||||
Domain | 412-448 | EGF-like | ||||
Sequence: DANECEAKPCVNARSCKNLIASYYCDCLPGWMGQNCD | ||||||
Domain | 450-485 | EGF-like | ||||
Sequence: NINDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCE | ||||||
Domain | 487-523 | EGF-like | ||||
Sequence: DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ | ||||||
Domain | 525-561 | EGF-like | ||||
Sequence: DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS | ||||||
Domain | 586-627 | EGF-like | ||||
Sequence: DTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCH | ||||||
Domain | 629-665 | EGF-like | ||||
Sequence: NINDCESNPCKNGGTCIDGVNSYKCICSDGWEGAHCE | ||||||
Domain | 667-703 | EGF-like | ||||
Sequence: NINDCSQNPCHYGGTCRDLVNDFYCDCKNGWKGKTCH | ||||||
Domain | 705-741 | EGF-like | ||||
Sequence: RDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCN | ||||||
Domain | 744-780 | EGF-like | ||||
Sequence: RNSSCLPNPCHNGGTCVVNGDSFTCVCKEGWEGPICT | ||||||
Domain | 782-818 | EGF-like | ||||
Sequence: NTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCR | ||||||
Domain | 820-856 | EGF-like | ||||
Sequence: NINECQSSPCAFGATCVDEINGYQCICPPGHSGAKCH | ||||||
Region | 1181-1218 | Disordered | ||||
Sequence: REEKAPSGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV | ||||||
Compositional bias | 1190-1209 | Polar residues | ||||
Sequence: PTKHPNWTNKQDNRDLESAQ |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,218
- Mass (Da)134,164
- Last updated2005-10-11 v1
- Checksum77739F8928BB793C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1190-1209 | Polar residues | ||||
Sequence: PTKHPNWTNKQDNRDLESAQ |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK137092 EMBL· GenBank· DDBJ | BAE23235.1 EMBL· GenBank· DDBJ | mRNA |