Q3UPM3 · Q3UPM3_MOUSE

  • Protein
    Dual specificity mitogen-activated protein kinase kinase 2
  • Gene
    Map2k2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site101ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentearly endosome
Cellular Componentfocal adhesion
Cellular Componentlate endosome
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processprotein phosphorylation
Biological Processregulation of early endosome to late endosome transport
Biological Processregulation of Golgi inheritance
Biological Processregulation of stress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity mitogen-activated protein kinase kinase 2
  • EC number
  • Alternative names
    • ERK activator kinase 2
    • MAPK/ERK kinase 2

Gene names

    • Name
      Map2k2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3UPM3

Organism-specific databases

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain72-244Protein kinase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    26,915
  • Last updated
    2005-10-11 v1
  • Checksum
    47C489B1D63A6161
MLARRKPVLPALTINPTIAEGPSPTSEGASEANLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTVMLFVVAGDLCPCI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK143425
EMBL· GenBank· DDBJ
BAE25372.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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