High-efficiency full-length cDNA cloning.Carninci P., Hayashizaki Y.Cited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMethods Enzymol 303:19-44 (1999)Cited in99+Mapped to15
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 10:1617-1630 (2000)Cited in199+Mapped to10
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K.[...], Togawa Y.View abstractCited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res 10:1757-1771 (2000)Cited in99+
Functional annotation of a full-length mouse cDNA collection.Kawai J., Shinagawa A., Shibata K., Yoshino M., Itoh M., Ishii Y., Arakawa T., Hara A., Fukunishi Y.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNature 409:685-690 (2001)Cited in399+Mapped to99+
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNature 420:563-573 (2002)Cited in699+Mapped to99+
No title available.Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K.[...], Hayashizaki Y.Cited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to EMBL/GenBank/DDBJ databases (MAR-2004)Cited in99+
The Transcriptional Landscape of the Mammalian Genome.The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)Cited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)Science 309:1559-1563 (2005)Cited in199+
Antisense transcription in the mammalian transcriptome.FANTOM ConsortiumKatayama S., Tomaru Y., Kasukawa T., Waki K., Nakanishi M., Nakamura M., Nishida H., Yap C.C., Suzuki M.[...], Wahlestedt C.View abstractCited forNUCLEOTIDE SEQUENCETissueLungCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCScience 309:1564-1566 (2005)Cited in99+
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice.Nakagawa O., Fujisawa K., Ishizaki T., Saito Y., Nakao K., Narumiya S.View abstractCategorySequencesSourceMGI: 107926PubMedEurope PMCFEBS Lett. 392:189-193 (1996)Cited in2Mapped to12
miR-101a-3p/ROCK2 axis regulates neuronal injury in Parkinson's disease models.Tao X., Zhang W., Chen C., Tao Y., Tao Y., Chen Z., Zhang G.View abstractAnnotationmiR-101a-3p/ROCK2 axis regulates neuronal injury in Parkinson's disease models.SourceGeneRif: 19878PubMedEurope PMCAging (Albany NY) 16:8732-8746 (2024)Mapped to7
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.Akamine T., Terabayashi T., Sasaki T., Hayashi R., Abe I., Hirayama F., Nureki S.I., Ikawa M., Miyata H.[...], Ishizaki T.View abstractSourceMGI: 107926PubMedEurope PMCFEBS Open Bio 14:906-921 (2024)Mapped to21
Deletion of podocyte Rho-associated, coiled-coil-containing protein kinase 2 protects mice from focal segmental glomerulosclerosis.Matoba K., Nagai Y., Sekiguchi K., Ohashi S., Mitsuyoshi E., Shimoda M., Tachibana T., Kawanami D., Yokota T.[...], Nishimura R.View abstractAnnotationDeletion of podocyte Rho-associated coiled-coil-containing protein kinase 2 protects mice from focal segmental glomerulosclerosis.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCCommun Biol 7:402-402 (2024)Mapped to7
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft- versus-host disease.Maas-Bauer K., Stell A.V., Yan K.L., de Vega E., Vinnakota J.M., Unger S., Nunez N., Norona J., Talvard-Balland N.[...], Zeiser R.View abstractAnnotationROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease.SourceGeneRif: 19878PubMedEurope PMCNat Commun 15:446-446 (2024)Mapped to16
Inhibition of microRNA-34c reduces detrusor ROCK2 expression and urinary bladder inflammation in experimental cystitis.Mandal M., Rakib A., Kiran S., Al Mamun M.A., Raghavan S., Kumar S., Singla B., Park F., Leo M.D., Singh U.P.View abstractAnnotationInhibition of microRNA-34c reduces detrusor ROCK2 expression and urinary bladder inflammation in experimental cystitis.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCLife Sci 336:122317-122317 (2024)Mapped to7
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.Cheng T., Agwu C., Shim K., Wang B., Jain S., Mahjoub M.R.View abstractCategoryFunctionSourceMGI: 107926PubMedEurope PMCDevelopment 150:dev201976-dev201976 (2023)Mapped to99+
A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex.Lee E., Chan S.L., Lee Y., Polacheck W.J., Kwak S., Wen A., Nguyen D.T., Kutys M.L., Alimperti S.[...], Chen C.S.View abstractAnnotationA 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCProc Natl Acad Sci U S A 120:e2308941120-e2308941120 (2023)Mapped to7
[Knock-down of ROCK2 gene improves cognitive function and reduces neuronal apoptosis in AD mice by promoting mitochondrial fusion and inhibiting its division].Guo M., Zhang H., Zhang P., Yu J., Meng T., Li S., Song L., Chai Z., Yu J., Ma C.View abstractSourceGeneRif: 19878PubMedEurope PMCXi Bao Yu Fen Zi Mian Yi Xue Za Zhi 39:701-707 (2023)Mapped to7
alpha-Actinin-4 recruits Shp2 into focal adhesions to potentiate ROCK2 activation in podocytes.Tseng C.C., Zheng R.H., Lin T.W., Chou C.C., Shih Y.C., Liang S.W., Lee H.H.View abstractAnnotationalpha-Actinin-4 recruits Shp2 into focal adhesions to potentiate ROCK2 activation in podocytes.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCLife Sci Alliance 5:e202201557-e202201557 (2022)Mapped to18
FOXO4 alleviates hippocampal neuronal damage in epileptic mice via the miR-138-5p/ROCK2 axis.Jin X., Liao X., Wu L., Huang J., Li Z., Li Y., Guo F.View abstractAnnotationFOXO4 alleviates hippocampal neuronal damage in epileptic mice via the miR-138-5p/ROCK2 axis.CategoriesFunction, ExpressionSourceGeneRif: 19878PubMedEurope PMCAm J Med Genet B Neuropsychiatr Genet 189:271-284 (2022)Mapped to11
Activity of ROCKII not ROCKI promotes pulmonary metastasis of melanoma cells via modulating Smad2/3-MMP9 and FAK-Src-VEGF signalling.Chatterjee S., Patra D., Ghosh P., Banerjee S., Chowdhury K.D., Chakraborty P., Basu A., Sadhukhan G.C.View abstractAnnotationActivity of ROCKII not ROCKI promotes pulmonary metastasis of melanoma cells via modulating Smad2/3-MMP9 and FAK-Src-VEGF signalling.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCCell Signal 97:110389-110389 (2022)Mapped to7
ROCK2-induced metabolic rewiring in diabetic podocytopathy.Matoba K., Takeda Y., Nagai Y., Sekiguchi K., Ukichi R., Takahashi H., Aizawa D., Ikegami M., Tachibana T.[...], Nishimura R.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 107926PubMedEurope PMCCommun Biol 5:341-341 (2022)Mapped to9
RhoA/ROCK2 signalling is enhanced by PDGF-AA in fibro-adipogenic progenitor cells: implications for Duchenne muscular dystrophy.Fernandez-Simon E., Suarez-Calvet X., Carrasco-Rozas A., Pinol-Jurado P., Lopez-Fernandez S., Pons G., Bech Serra J.J., de la Torre C., de Luna N.[...], Diaz-Manera J.View abstractAnnotationRhoA/ROCK2 signalling is enhanced by PDGF-AA in fibro-adipogenic progenitor cells: implications for Duchenne muscular dystrophy.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCJ Cachexia Sarcopenia Muscle 13:1373-1384 (2022)Mapped to10
Conditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons.Weber A.J., Adamson A.B., Greathouse K.M., Andrade J.P., Freeman C.D., Seo J.V., Rae R.J., Walker C.K., Herskowitz J.H.View abstractAnnotationConditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 19878, MGI: 107926PubMedEurope PMCMol Brain 14:169-169 (2021)Mapped to9
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes.Scheiblich H., Dansokho C., Mercan D., Schmidt S.V., Bousset L., Wischhof L., Eikens F., Odainic A., Spitzer J.[...], Heneka M.T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 107926PubMedEurope PMCCell 184:5089-5106.e21 (2021)Mapped to30
Exercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice.Munoz V.R., Gaspar R.C., Severino M.B., Macedo A.P.A., Simabuco F.M., Ropelle E.R., Cintra D.E., da Silva A.S.R., Kim Y.B., Pauli J.R.View abstractAnnotationExercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice.CategoryFunctionSourceGeneRif: 19878PubMedEurope PMCFront Immunol 12:702025-702025 (2021)Mapped to7