Q3UK05 · Q3UK05_MOUSE

  • Protein
    Dual specificity mitogen-activated protein kinase kinase 1
  • Gene
    Map2k1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site97ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcentrosome
Cellular Componentearly endosome
Cellular Componentfocal adhesion
Cellular Componentlate endosome
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentspindle pole body
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processprotein phosphorylation
Biological Processregulation of early endosome to late endosome transport
Biological Processregulation of Golgi inheritance
Biological Processregulation of stress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity mitogen-activated protein kinase kinase 1
  • EC number
  • Alternative names
    • ERK activator kinase 1
    • MAPK/ERK kinase 1

Gene names

    • Name
      Map2k1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DBA/2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3UK05

Organism-specific databases

PTM/Processing

Keywords

Proteomic databases

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-27Disordered
Domain68-361Protein kinase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    393
  • Mass (Da)
    43,504
  • Last updated
    2005-10-11 v1
  • Checksum
    770ABB39C47521E2
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPTIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK146233
EMBL· GenBank· DDBJ
BAE26999.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp