Dietary energy tissue-specifically regulates endoplasmic reticulum chaperone gene expression in the liver of mice.Dhahbi J.M., Mote P.L., Tillman J.B., Walford R.L., Spindler S.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95835PubMedEurope PMCJ Nutr 127:1758-1764 (1997)Mapped to13
Chromosomal localization of five murine HSP70 gene family members: Hsp70- 1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.Hunt C.R., Gasser D.L., Chaplin D.D., Pierce J.C., Kozak C.A.View abstractCategorySequencesSourceMGI: 95835PubMedEurope PMCGenomics 16:193-198 (1993)Mapped to50
Genetic aspects of the hsp70 multigene family in vertebrates.Gunther E., Walter L.View abstractCategorySequencesSourceMGI: 95835PubMedEurope PMCExperientia 50:987-1001 (1994)Mapped to35
Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8 gamma chain, prostaglandin-D-synthase, oncogene-24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2.Chan P., Simon-Chazottes D., Mattei M.G., Guenet J.L., Salier J.P.View abstractCategorySequencesSourceMGI: 95835PubMedEurope PMCGenomics 23:145-150 (1994)Mapped to22
Stathmin interaction with a putative kinase and coiled-coil-forming protein domains.Maucuer A., Camonis J.H., Sobel A.View abstractCategoriesSequences, InteractionSourceMGI: 95835PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 92:3100-3104 (1995)Cited in31Mapped to40
Structure and regulation of the mouse GRP78 (BiP) promoter by glucose and calcium ionophore.Tillman J.B., Mote P.L., Walford R.L., Spindler S.R.View abstractCategorySequencesSourceMGI: 95835PubMedEurope PMCGene 158:225-229 (1995)Cited in1Mapped to10
Piezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway.Xie D., Ma Y., Gao C., Pan S.View abstractAnnotationPiezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway.SourceGeneRif: 14828PubMedEurope PMCInt Immunopharmacol 142:113045-113045 (2024)Mapped to23
Grp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH.Shoup D., Priola S.A.View abstractAnnotationGrp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCJ Biol Chem 300:107346-107346 (2024)Mapped to10
GRP78 Contributes to the Beneficial Effects of SGLT2 Inhibitor on Proximal Tubular Cells in DKD.Nakatsuka A., Yamaguchi S., Wada J.View abstractAnnotationGRP78 Contributes to the Beneficial Effects of SGLT2 Inhibitor on Proximal Tubular Cells in DKD.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCDiabetes 73:763-779 (2024)Mapped to10
Pirh2 modulates amyloid-beta aggregation through the regulation of glucose-regulated protein 78 and chaperone-mediated signaling.Singh A., Tiwari S., Singh S.View abstractAnnotationPirh2 modulates amyloid-beta aggregation through the regulation of glucose-regulated protein 78 and chaperone-mediated signaling.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCJ Cell Physiol 238:2841-2854 (2023)Mapped to13
Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma.Zhao T., Jiang T., Li X., Chang S., Sun Q., Kong F., Kong X., Wei F., He J.[...], Xie K.View abstractAnnotationNuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCClin Cancer Res 29:5183-5195 (2023)Mapped to13
Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.Spaan C.N., de Boer R.J., Smit W.L., van der Meer J.H., van Roest M., Vermeulen J.L., Koelink P.J., Becker M.A., Go S.[...], Heijmans J.View abstractAnnotationGrp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.CategoryFunctionSourceGeneRif: 14828, MGI: 95835PubMedEurope PMCLife Sci Alliance 6:e202301912-e202301912 (2023)Mapped to19
The ER chaperone, BIP protects Microglia from ER stress-mediated Apoptosis in Hyperglycemia.James A.W., Bahader G.A., Albassan M., Shah Z.A.View abstractAnnotationThe ER chaperone BIP protects Microglia from ER stress-mediated Apoptosis in Hyperglycemia.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCNeurochem Int 169:105573-105573 (2023)Mapped to13
The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice.Espina M., Di Franco N., Branas-Navarro M., Navarro I.R., Brito V., Lopez-Molina L., Costas-Insua C., Guzman M., Gines S.View abstractAnnotationThe GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCNeurobiol Dis 184:106225-106225 (2023)Mapped to14
Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.Xu J., Yang C., Zeng S., Wang X., Yang P., Qin L.View abstractAnnotationDisturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCJ Neuroinflammation 20:150-150 (2023)Mapped to13
Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.Fukawa M., Shirai R., Torii T., Nakata K., Fukatsu S., Sato T., Homma K., Miyamoto Y., Yamauchi J.View abstractAnnotationExtracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCBiochem Biophys Res Commun 664:50-58 (2023)Mapped to10
Endoplasmic reticulum chaperone GRP78 participates in fluoride-induced autophagy in LS8 cells by regulating the IRE1-TRAF2-JNK pathway.Zhao L., Wang L., Wang H., Xi T., Liu S., Li Y., Ruan J., Huang Y.View abstractAnnotationEndoplasmic reticulum chaperone GRP78 participates in fluoride-induced autophagy in LS8 cells by regulating the IRE1-TRAF2-JNK pathway.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCEnviron Toxicol 38:1756-1767 (2023)Mapped to24
Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of <i>Dab1</i><sup>-/-</sup><i>(yotari</i>) Mice.Maglica M., Kelam N., Haque E., Perutina I., Racetin A., Filipovic N., Katsuyama Y., Vukojevic K.View abstractCategoryFunctionSourceMGI: 95835PubMedEurope PMCBiomolecules 13:402-402 (2023)Mapped to48
The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development.Lee E.S., Aryal Y.P., Kim T.Y., Pokharel E., Kim J.Y., Yamamoto H., An C.H., An S.Y., Jung J.K.[...], Kim J.Y.View abstractCategoryFunctionSourceMGI: 95835PubMedEurope PMCFront Physiol 13:1079355-1079355 (2022)Mapped to16
The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway.Shao Y., Xu Y., Di H., Shi X., Wang Y., Liu H., Song L.View abstractAnnotationThe inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway.CategoriesFunction, ExpressionSourceGeneRif: 14828PubMedEurope PMCIET Nanobiotechnol 17:182-196 (2023)Mapped to20
Conditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice.Wen Z., Zhu H., Wang J., Wu B., Zhang A., Zhao H., Song C., Liu S., Cheng Y.[...], Liu M.View abstractAnnotationConditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14828PubMedEurope PMCLife Sci 314:121319-121319 (2023)Mapped to10
Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy.Brentville V.A., Symonds P., Chua J., Skinner A., Daniels I., Cook K.W., Koncarevic S., Martinez-Pinna R., Shah S.[...], Durrant L.G.View abstractAnnotationCitrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy.CategoriesFunction, PTM / ProcessingSourceGeneRif: 14828, MGI: 95835PubMedEurope PMCFront Immunol 13:1066185-1066185 (2022)Mapped to42
Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis.Chen H.S., Wang J., Li H.H., Wang X., Zhang S.Q., Deng T., Li Y.K., Zou R.S., Wang H.J.[...], Chen J.G.View abstractAnnotationLong noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis.CategoryFunctionSourceGeneRif: 14828PubMedEurope PMCSci Adv 8:eabn2496-eabn2496 (2022)Mapped to10
The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat.Ting J., Wooden S.K., Kriz R., Kelleher K., Kaufman R.J., Lee A.S.View abstractCategorySequencesSourceMGI: 95835PubMedEurope PMCGene 55:147-152 (1987)Cited in1Mapped to11
ER stress transforms random olfactory receptor choice into axon targeting precision.Shayya H.J., Kahiapo J.K., Duffie R., Lehmann K.S., Bashkirova L., Monahan K., Dalton R.P., Gao J., Jiao S.[...], Lomvardas S.View abstractCategoryFunctionSourceMGI: 95835PubMedEurope PMCCell 185:3896-3912.e22 (2022)Mapped to33