Specificity of the SH2 domains of SHP-1 in the interaction with the immunoreceptor tyrosine-based inhibitory motif-bearing receptor gp49B.Wang L.L., Blasioli J., Plas D.R., Thomas M.L., Yokoyama W.M.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCJ. Immunol. 162:1318-1323 (1999)Cited in2Mapped to11
The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells.Huber M., Izzi L., Grondin P., Houde C., Kunath T., Veillette A., Beauchemin N.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCJ. Biol. Chem. 274:335-344 (1999)Cited in3Mapped to21
The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate.Berg K.L., Carlberg K., Rohrschneider L.R., Siminovitch K.A., Stanley E.R.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCOncogene 17:2535-2541 (1998)Mapped to14
SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity.Yang W., Mckenna S.D., Jiao H., Tabrizi M., Lynes M.A., Shultz L.D., Yi T.View abstractCategoriesFunctionSourceMGI: 96055PubMedEurope PMCExp Hematol 26:1126-1132 (1998)Mapped to13
The protein tyrosine phosphatase SHP-1 regulates integrin-mediated adhesion of macrophages.Roach T.I., Slater S.E., White L.S., Zhang X., Majerus P.W., Brown E.J., Thomas M.L.View abstractCategoriesFunctionSourceMGI: 96055PubMedEurope PMCCurr Biol 8:1035-1038 (1998)Mapped to17
High expression of inhibitory receptor SHPS-1 and its association with protein tyrosine phosphatase SHP-1 in macrophages.Veillette A., Thibaudeau E., Latour S.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCJ. Biol. Chem. 273:22719-22728 (1998)Cited in3Mapped to14
Functional consequences of the SHP-1 defect in motheaten viable mice: role of NF-kappa B.Khaled A.R., Butfiloski E.J., Sobel E.S., Schiffenbauer J.View abstractCategoriesFunctionSourceMGI: 96055PubMedEurope PMCCell Immunol 185:49-58 (1998)Mapped to13
Aberrant regulation of bone trace elements in motheaten and osteopetrosis mutant mice.Yamada G., Nakamura S., Haraguchi R., Sakai M., Suzuki K., Miyado K., Hasuwa H., Ogino Y., Minami T.[...], Shultz L.D.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCCell Mol Biol (Noisy-le-grand) 44:315-319 (1998)Mapped to15
A comparative analysis of the murine thymic microenvironment in normal, autoimmune, and immunodeficiency states.Takeoka Y., Chen S.Y., Boyd R.L., Tsuneyama K., Taguchi N., Morita S., Yago H., Suehiro S., Ansari A.A.[...], Gershwin M.E.View abstractCategoriesSequencesSourceMGI: 96055PubMedEurope PMCDev Immunol 5:79-89 (1997)Mapped to11
Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.Cornall R.J., Cyster J.G., Hibbs M.L., Dunn A.R., Otipoby K.L., Clark E.A., Goodnow C.C.View abstractCategoriesFunctionSourceMGI: 96055PubMedEurope PMCImmunity 8:497-508 (1998)Mapped to25
SHP-1 phosphatase C-terminus interacts with novel substrates p32/p30 during erythropoietin and interleukin-3 mitogenic responses.Yang W., Tabrizi M., Berrada K., Yi T.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCBlood 91:3746-3755 (1998)Mapped to8
Abnormal development and differentiation of macrophages and dendritic cells in viable motheaten mutant mice deficient in haematopoietic cell phosphatase.Nakayama K., Takahashi K., Shultz L.D., Miyakawa K., Tomita K.View abstractCategoriesExpressionSourceMGI: 96055PubMedEurope PMCInt J Exp Pathol 78:245-257 (1997)Mapped to8
Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5- phosphatase SHIP with gp49B1, and chromosomal assignment of the gene.Kuroiwa A., Yamashita Y., Inui M., Yuasa T., Ono M., Nagabukuro A., Matsuda Y., Takai T.View abstractCategoriesSequencesSourceMGI: 96055PubMedEurope PMCJ. Biol. Chem. 273:1070-1074 (1998)Cited in1Mapped to21
Role of tumor necrosis factor-alpha in the spontaneous development of pulmonary fibrosis in viable motheaten mutant mice.Thrall R.S., Vogel S.N., Evans R., Shultz L.D.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96055PubMedEurope PMCAm J Pathol 151:1303-1310 (1997)Mapped to14
DNA-binding antibodies from viable motheaten mutant mice: implications for B cell tolerance.Westhoff C.M., Whittier A., Kathol S., McHugh J., Zajicek C., Shultz L.D., Wylie D.E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCJ Immunol 159:3024-3033 (1997)Mapped to8
Severe defects in immunity and hematopoiesis caused by SHP-1 protein- tyrosine-phosphatase deficiency.Shultz L.D., Rajan T.V., Greiner D.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCTrends Biotechnol 15:302-307 (1997)Mapped to8
The motheaten mutation rescues B cell signaling and development in CD45- deficient mice.Pani G., Siminovitch K.A., Paige C.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCJ Exp Med 186:581-588 (1997)Mapped to41
Macrophages from motheaten and viable motheaten mutant mice show increased proliferative responses to GM-CSF: detection of potential HCP substrates in GM-CSF signal transduction.Jiao H., Yang W., Berrada K., Tabrizi M., Shultz L., Yi T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCExp Hematol 25:592-600 (1997)Mapped to11
Restricted CDR3 length of the heavy chain is characteristic of six randomly isolated disease-associated VH J558+ IgM autoantibodies in lupus prone motheaten mice.Lipsanen V., Walter B., Emara M., Siminovitch K., Lam J., Kaushik A.View abstractCategoriesSequencesSourceMGI: 96055PubMedEurope PMCInt Immunol 9:655-664 (1997)Mapped to11
Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.Yamao T., Matozaki T., Amano K., Matsuda Y., Takahashi N., Ochi F., Fujioka Y., Kasuga M.View abstractCategoriesSequencesSourceMGI: 96055PubMedEurope PMCBiochem. Biophys. Res. Commun. 231:61-67 (1997)Cited in2Mapped to16
Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1.Lorenz U., Bergemann A.D., Steinberg H.N., Flanagan J.G., Li X., Galli S.J., Neel B.G.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96055PubMedEurope PMCJ Exp Med 184:1111-1126 (1996)Mapped to11
Association of biliary glycoprotein with protein tyrosine phosphatase SHP- 1 in malignant colon epithelial cells.Beauchemin N., Kunath T., Robitaille J., Chow B., Turbide C., Daniels E., Veillette A.View abstractCategoriesFunction, InteractionSourceMGI: 96055PubMedEurope PMCOncogene 14:783-790 (1997)Mapped to20
Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase.Nakamura M.C., Niemi E.C., Fisher M.J., Shultz L.D., Seaman W.E., Ryan J.C.View abstractCategoriesFunction, SequencesSourceMGI: 96055PubMedEurope PMCJ Exp Med 185:673-684 (1997)Mapped to8
Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1.Piao X., Paulson R., van der Geer P., Pawson T., Bernstein A.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 96055PubMedEurope PMCProc Natl Acad Sci U S A 93:14665-14669 (1996)Mapped to11
Direct association with and dephosphorylation of Jak2 kinase by the SH2- domain-containing protein tyrosine phosphatase SHP-1.Jiao H., Berrada K., Yang W., Tabrizi M., Platanias L.C., Yi T.View abstractCategoriesInteractionSourceMGI: 96055PubMedEurope PMCMol Cell Biol 16:6985-6992 (1996)Mapped to35