Q3U8K3 · Q3U8K3_MOUSE
- ProteinDual specificity protein phosphatase
- GeneDusp1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids367 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 258 | Phosphocysteine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | MAP kinase tyrosine/serine/threonine phosphatase activity | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein tyrosine phosphatase activity | |
Biological Process | cellular response to chemokine | |
Biological Process | negative regulation of cell adhesion | |
Biological Process | negative regulation of MAP kinase activity | |
Biological Process | negative regulation of monocyte chemotaxis | |
Biological Process | negative regulation of p38MAPK cascade | |
Biological Process | peptidyl-tyrosine dephosphorylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity protein phosphatase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ3U8K3
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 20-137 | Rhodanese | |||
Domain | 173-314 | Tyrosine-protein phosphatase | |||
Domain | 238-292 | Tyrosine specific protein phosphatases | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length367
- Mass (Da)39,370
- Last updated2005-10-11 v1
- Checksum50B5F90FEBBD19AB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK149915 EMBL· GenBank· DDBJ | BAE29163.1 EMBL· GenBank· DDBJ | mRNA | ||
AK152183 EMBL· GenBank· DDBJ | BAE31014.1 EMBL· GenBank· DDBJ | mRNA | ||
AK152324 EMBL· GenBank· DDBJ | BAE31126.1 EMBL· GenBank· DDBJ | mRNA | ||
AK159251 EMBL· GenBank· DDBJ | BAE34932.1 EMBL· GenBank· DDBJ | mRNA | ||
AK159363 EMBL· GenBank· DDBJ | BAE35021.1 EMBL· GenBank· DDBJ | mRNA | ||
AK159567 EMBL· GenBank· DDBJ | BAE35190.1 EMBL· GenBank· DDBJ | mRNA | ||
AK159658 EMBL· GenBank· DDBJ | BAE35267.1 EMBL· GenBank· DDBJ | mRNA | ||
AK159726 EMBL· GenBank· DDBJ | BAE35320.1 EMBL· GenBank· DDBJ | mRNA | ||
AK167602 EMBL· GenBank· DDBJ | BAE39659.1 EMBL· GenBank· DDBJ | mRNA | ||
AK168627 EMBL· GenBank· DDBJ | BAE40487.1 EMBL· GenBank· DDBJ | mRNA |