Q3U8K3 · Q3U8K3_MOUSE

  • Protein
    Dual specificity protein phosphatase
  • Gene
    Dusp1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site258Phosphocysteine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionMAP kinase tyrosine/serine/threonine phosphatase activity
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein tyrosine phosphatase activity
Biological Processcellular response to chemokine
Biological Processnegative regulation of cell adhesion
Biological Processnegative regulation of MAP kinase activity
Biological Processnegative regulation of monocyte chemotaxis
Biological Processnegative regulation of p38MAPK cascade
Biological Processpeptidyl-tyrosine dephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity protein phosphatase
  • EC number

Gene names

    • Name
      Dusp1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3U8K3

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Expression

Gene expression databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain20-137Rhodanese
Domain173-314Tyrosine-protein phosphatase
Domain238-292Tyrosine specific protein phosphatases

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    367
  • Mass (Da)
    39,370
  • Last updated
    2005-10-11 v1
  • Checksum
    50B5F90FEBBD19AB
MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK149915
EMBL· GenBank· DDBJ
BAE29163.1
EMBL· GenBank· DDBJ
mRNA
AK152183
EMBL· GenBank· DDBJ
BAE31014.1
EMBL· GenBank· DDBJ
mRNA
AK152324
EMBL· GenBank· DDBJ
BAE31126.1
EMBL· GenBank· DDBJ
mRNA
AK159251
EMBL· GenBank· DDBJ
BAE34932.1
EMBL· GenBank· DDBJ
mRNA
AK159363
EMBL· GenBank· DDBJ
BAE35021.1
EMBL· GenBank· DDBJ
mRNA
AK159567
EMBL· GenBank· DDBJ
BAE35190.1
EMBL· GenBank· DDBJ
mRNA
AK159658
EMBL· GenBank· DDBJ
BAE35267.1
EMBL· GenBank· DDBJ
mRNA
AK159726
EMBL· GenBank· DDBJ
BAE35320.1
EMBL· GenBank· DDBJ
mRNA
AK167602
EMBL· GenBank· DDBJ
BAE39659.1
EMBL· GenBank· DDBJ
mRNA
AK168627
EMBL· GenBank· DDBJ
BAE40487.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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