Q3U350 · Q3U350_MOUSE

  • Protein
    Serine/threonine-protein kinase
  • Gene
    Ulk1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Serine/threonine-protein kinase involved in autophagy in response to starvation.

Catalytic activity

Features

Showing features for binding site.

110511002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site46ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentautophagosome
Cellular Componentcytosol
Cellular Componentphagophore assembly site membrane
Molecular FunctionATP binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processautophagosome assembly
Biological Processautophagy of mitochondrion
Biological Processaxon extension
Biological Processnegative regulation of collateral sprouting
Biological Processpiecemeal microautophagy of the nucleus
Biological Processpositive regulation of autophagy
Biological Processresponse to starvation
Biological Processreticulophagy
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase
  • EC number

Gene names

    • Name
      Ulk1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NOD
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3U350

Organism-specific databases

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain16-278Protein kinase
Region283-323Disordered
Compositional bias296-323Polar residues
Region335-358Disordered
Region394-554Disordered
Compositional bias435-475Polar residues
Region661-686Disordered
Region727-787Disordered
Compositional bias759-787Polar residues

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,051
  • Mass (Da)
    112,467
  • Last updated
    2005-10-11 v1
  • Checksum
    5069D0769B9FFD1A
MEPGRGGVETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPAIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASTPIKKSPPVPVPSYPSSGSGSSSSSSSASHLASPPSLGEMPQLQKTLTSPADAAGFLQGSRDSGGSSKDSCDTDDFVMVPAQFPGDLVAEAASAKPPPDSLLCSGSSLVASAGLESHGRTPSPSPTCSSSPSPSGRPGPFSSNRYGASVPIPVPTQVHNYQRIEQNLQSPTQQQTARSSAIRRSGSTSPLGFGRASPSPPSHTDGAMLARKLSLGGGRPYTPSPQVGTIPERPSWSRVPSPQGADVRVGRSPRPGSSVPEHSPRTTGLGCRLHSAPNLSDFHVVRPKLPKPPTDPLGATFSPPQTSAPQPCPGLQSCRPLRGSPKLPDFLQRSPLPPILGSPTKAGPSFDFPKTPSSQNLLTLLARQGVVMTPPRNRTLPDLSEASPFHGQQLGSGLRPAEDTRGPFGRSFSTSRITDLLLKAAFGTQASDSGSTDSLQEKPMEIAPSAGFGGTLHPGARGGGASSPAPVVFTVGSPPSGATPPQSTRTRMFSVGSSSSLGSTGSSSARHLVPGACGEAPELSAPGHCCSLADPLAANLEGAVTFEAPDLPEETLMEQEHTETLHSLRFTLAFAQQVLEIAALKGSASEAAGGPEYQLQESVVADQISQLSREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNEMYKASVVSCQGLSLRLQRFFLDKQRLLDGIHGVTAERLILSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHTLTDQADIENIAKCKLCIERRLSALLSGVYA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias296-323Polar residues
Compositional bias435-475Polar residues
Compositional bias759-787Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK154939
EMBL· GenBank· DDBJ
BAE32939.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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