Loss of LKLF function results in embryonic lethality in mice.Wani M.A., Means R.T. Jr., Lingrel J.B.View abstractCategoriesFunction, ExpressionSourceMGI: 95663PubMedEurope PMCTransgenic Res 7:229-238 (1998)Mapped to16
TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3.Ono Y., Fukuhara N., Yoshie O.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCMol. Cell. Biol. 18:6939-6950 (1998)Cited in11Mapped to21
Jak2 is essential for signaling through a variety of cytokine receptors.Parganas E., Wang D., Stravopodis D., Topham D.J., Marine J.C., Teglund S., Vanin E.F., Bodner S., Colamonici O.R.[...], Ihle J.N.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCCell 93:385-395 (1998)Cited in1Mapped to99+
Knock-in mutation of transcription factor GATA-3 into the GATA-1 locus: partial rescue of GATA-1 loss of function in erythroid cells.Tsai F.Y., Browne C.P., Orkin S.H.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCDev Biol 196:218-227 (1998)Mapped to9
Transcription factor GATA-3 is required for development of the T-cell lineage.Ting C.N., Olson M.C., Barton K.P., Leiden J.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95663PubMedEurope PMCNature 384:474-478 (1996)Mapped to6
Restraint of IFN-gamma expression through a distal silencer CNS-28 for tissue homeostasis.Cui K., Chen Z., Cao Y., Liu S., Ren G., Hu G., Fang D., Wei D., Liu C.[...], Zhao K.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCImmunity 56:944-958.e6 (2023)Mapped to13
Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development.De Bono C., Liu Y., Ferrena A., Valentine A., Zheng D., Morrow B.E.View abstractCategoriesFunction, ExpressionSourceMGI: 95663PubMedEurope PMCNat Commun 14:1551-1551 (2023)Mapped to73
Crosstalk between ILC2s and Th2 cells varies among mouse models.Gurram R.K., Wei D., Yu Q., Butcher M.J., Chen X., Cui K., Hu G., Zheng M., Zhu X.[...], Zhu J.View abstractCategoriesFunction, ExpressionSourceMGI: 95663PubMedEurope PMCCell Rep 42:112073-112073 (2023)Mapped to18
DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.Chen G.D., Fatima I., Xu Q., Rozhkova E., Fessing M.Y., Mardaryev A.N., Sharov A.A., Xu G.L., Botchkarev V.A.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCSci Adv 9:eabo7605-eabo7605 (2023)Mapped to61
Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development.Song H., Morrow B.E.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCDev Biol 494:71-84 (2023)Mapped to89
Setd2 supports GATA3<sup>+</sup>ST2<sup>+</sup> thymic-derived Treg cells and suppresses intestinal inflammation.Ding Z., Cai T., Tang J., Sun H., Qi X., Zhang Y., Ji Y., Yuan L., Chang H.[...], Qiu J.View abstractAnnotationSetd2 supports GATA3[+]CategoriesFunctionSourceGeneRif: 14462, MGI: 95663PubMedEurope PMCNat Commun 13:7468-7468 (2022)Mapped to31
GATA3 mediates nonclassical beta-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis.Maruyama T., Hasegawa D., Valenta T., Haigh J., Bouchard M., Basler K., Hsu W.View abstractAnnotationGATA3 mediates nonclassical beta-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis.CategoriesFunctionSourceGeneRif: 14462, MGI: 95663PubMedEurope PMCSci Adv 8:eadd6172-eadd6172 (2022)Mapped to45
<i>Brca1</i> Is Regulated by the Transcription Factor <i>Gata3</i>, and Its Silencing Promotes Neural Differentiation in Retinal Neurons.Zhuang J., Chen P., Wu Y., Luo Q., Wang Q., Chen S., Chen X., Jiang Z., Qiu J.[...], Zhuang J.View abstractAnnotationBrca1 Is Regulated by the Transcription Factor Gata3 and Its Silencing Promotes Neural Differentiation in Retinal Neurons.CategoriesFunction, ExpressionSourceGeneRif: 14462PubMedEurope PMCInt J Mol Sci 23:13860-13860 (2022)Mapped to44
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons.Hummel D., Becks A., Men H., Bryda E.C., Glasco D.M., Chandrasekhar A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95663PubMedEurope PMCDevelopment 149:dev200553-dev200553 (2022)Mapped to25
Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response.Jiao W.E., Xu S., Qiao Y.L., Kong Y.G., Sun L., Deng Y.Q., Yang R., Tao Z.Z., Hua Q.Q., Chen S.M.View abstractAnnotationNotch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14462, MGI: 95663PubMedEurope PMCInt Immunopharmacol 112:109261-109261 (2022)Mapped to16
ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization.Filova I., Pysanenko K., Tavakoli M., Vochyanova S., Dvorakova M., Bohuslavova R., Smolik O., Fabriciova V., Hrabalova P.[...], Pavlinkova G.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95663PubMedEurope PMCProc Natl Acad Sci U S A 119:e2207433119-e2207433119 (2022)Mapped to99+
Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation.Zaidan N., Nitsche L., Diamanti E., Hannah R., Fidanza A., Wilson N.K., Forrester L.M., Gottgens B., Ottersbach K.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCStem Cell Reports 17:1788-1798 (2022)Mapped to23
Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons.Kirjavainen A., Singh P., Lahti L., Seja P., Lelkes Z., Makkonen A., Kilpinen S., Ono Y., Salminen M.[...], Partanen J.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCDevelopment 149:dev200937-dev200937 (2022)Mapped to98
NANOG initiates epiblast fate through the coordination of pluripotency genes expression.Allegre N., Chauveau S., Dennis C., Renaud Y., Meistermann D., Estrella L.V., Pouchin P., Cohen-Tannoudji M., David L., Chazaud C.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCNat Commun 13:3550-3550 (2022)Mapped to99+
Immunoproteasome Inhibition Reduces the T Helper 2 Response in Mouse Models of Allergic Airway Inflammation.Oliveri F., Basler M., Rao T.N., Fehling H.J., Groettrup M.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCFront Immunol 13:870720-870720 (2022)Mapped to15
c-Maf enforces cytokine production and promotes memory-like responses in mouse and human type 2 innate lymphoid cells.Trabanelli S., Ercolano G., Wyss T., Gomez-Cadena A., Falquet M., Cropp D., Imbratta C., Leblond M.M., Salvestrini V.[...], Verdeil G.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCEMBO J 41:e109300-e109300 (2022)Mapped to14
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.Hertweck A., Vila de Mucha M., Barber P.R., Dagil R., Porter H., Ramos A., Lord G.M., Jenner R.G.View abstractAnnotationThe TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.CategoriesFunctionSourceGeneRif: 14462PubMedEurope PMCNucleic Acids Res 50:4557-4573 (2022)Mapped to7
Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii- induced neuroinflammation.Steffen J., Ehrentraut S., Bank U., Biswas A., Figueiredo C.A., Holsken O., Dusedau H.P., Dovhan V., Knop L.[...], Dunay I.R.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCCell Rep 38:110564-110564 (2022)Mapped to19
Metabotropic glutamate receptor 5 upregulation of gamma-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.Xu P., Huang X., Niu W., Yu D., Zhou M., Wang H.View abstractAnnotationMetabotropic glutamate receptor 5 upregulation of gamma-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice.CategoriesFunctionSourceGeneRif: 14462PubMedEurope PMCBrain Res Bull 183:104-115 (2022)Mapped to13
Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism.Duethorn B., Groll F., Rieger B., Drexler H.C.A., Brinkmann H., Kremer L., Stehling M., Borowski M.T., Mildner K.[...], Bedzhov I.View abstractCategoriesFunctionSourceMGI: 95663PubMedEurope PMCNat Commun 13:610-610 (2022)Mapped to56