RGS3 may provide protection against pathological changes of adventitial fibroblasts and the development of atherosclerosis by inhibiting TGF-beta1/Smad signaling.
Results reveal an essential role of PDZ-RGS3 in maintaining the balance between self-renewal and differentiation of neural progenitor cells and provide genetic evidence linking PDZ-RGS3 to ephrin-B reverse signaling.
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