RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.Mizuta R., LaSalle J.M., Cheng H.-L., Shinohara A., Ogawa H., Copeland N.G., Jenkins N.A., Lalande M., Alt F.W.View abstractCategoriesSequences, InteractionSourceMGI: 88335PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 94:6927-6932 (1997)Cited in2Mapped to44
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.Chu K., Niu X., Williams L.T.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 92:11894-11898 (1995)Cited in1Mapped to12
Interactions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeast.Campbell K.S., Buder A., Deuschle U.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCEur J Immunol 25:2408-2412 (1995)Mapped to16
ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells.van Oers N.S., Killeen N., Weiss A.View abstractCategoriesPTM / Processing, InteractionSourceMGI: 88335PubMedEurope PMCImmunity 1:675-685 (1994)Mapped to7
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.Behrens G., Edelmann S.L., Raj T., Kronbeck N., Monecke T., Davydova E., Wong E.H., Kifinger L., Giesert F.[...], Heissmeyer V.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCNat Immunol 22:1563-1576 (2021)Mapped to32
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck.Veillette A., Bookman M.A., Horak E.M., Bolen J.B.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCCell 55:301-308 (1988)Cited in1Mapped to7
The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain <i>Cd4</i> silencing in cytotoxic T cells.Ng C., Aichinger M., Nguyen T., Au C., Najar T., Wu L., Mesa K.R., Liao W., Quivy J.P.[...], Littman D.R.View abstractAnnotationCAF-1 and the DNA methyltransferases cooperate to maintain Cd4 silencing and thereby contribute to CD8+ T-cell function and lineage integrityCategoriesFunction, InteractionSourceGeneRif: 12504, MGI: 88335PubMedEurope PMCGenes Dev 33:669-683 (2019)Mapped to29
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.Rehage N., Davydova E., Conrad C., Behrens G., Maiser A., Stehklein J.E., Brenner S., Klein J., Jeridi A.[...], Heissmeyer V.View abstractCategoriesFunction, InteractionSourceMGI: 88335PubMedEurope PMCNat Commun 9:299-299 (2018)Mapped to39
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.Essig K., Hu D., Guimaraes J.C., Alterauge D., Edelmann S., Raj T., Kranich J., Behrens G., Heiseke A.[...], Heissmeyer V.View abstractCategoriesFunction, InteractionSourceMGI: 88335PubMedEurope PMCImmunity 47:1067-1082.e12 (2017)Mapped to39
Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.Janowski R., Heinz G.A., Schlundt A., Wommelsdorf N., Brenner S., Gruber A.R., Blank M., Buch T., Buhmann R.[...], Sattler M.View abstractCategoriesFunction, InteractionSourceMGI: 88335PubMedEurope PMCNat. Commun. 7:11032-11032 (2016)Cited in1Mapped to15
The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck.Roh K.H., Lillemeier B.F., Wang F., Davis M.M.View abstractAnnotationCD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lckCategoriesFunction, Interaction, Subcellular LocationSourceGeneRif: 12504, MGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 112:E1604-13 (2015)Mapped to9
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.Van Laethem F., Tikhonova A.N., Pobezinsky L.A., Tai X., Kimura M.Y., Le Saout C., Guinter T.I., Adams A., Sharrow S.O.[...], Singer A.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCCell 154:1326-1341 (2013)Mapped to30
The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma.Yagi R., Junttila I.S., Wei G., Urban J.F. Jr., Zhao K., Paul W.E., Zhu J.View abstractCategoriesInteractionSourceMGI: 88335PubMedEurope PMCImmunity 32:507-517 (2010)Mapped to35
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.Vondenhoff M.F., Greuter M., Goverse G., Elewaut D., Dewint P., Ware C.F., Hoorweg K., Kraal G., Mebius R.E.View abstractCategoriesFunction, Expression, InteractionSourceMGI: 88335PubMedEurope PMCJ Immunol 182:5439-5445 (2009)Mapped to74
Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity.Miceli M.C., von Hoegen P., Parnes J.R.View abstractCategoriesFunction, Interaction, Subcellular LocationSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 88:2623-2627 (1991)Mapped to4
Triggering of T cell activation via CD4 dimers.Moldovan M.C., Sabbagh L., Breton G., Sekaly R.P., Krummel M.F.View abstractAnnotationmodulation of the dimer/monomer of CD4 ratio may permit tuning of activation thresholds during initial engagementCategoriesInteractionSourceGeneRif: 12504, MGI: 88335PubMedEurope PMCJ Immunol 176:5438-5445 (2006)Mapped to5
Microtubule-associated protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4).Suzuki M., Hirao A., Mizuno A.View abstractCategoriesInteraction, Subcellular LocationSourceMGI: 88335PubMedEurope PMCJ. Biol. Chem. 278:51448-51453 (2003)Cited in2Mapped to14
Ligation of human CD4 interferes with antigen-induced activation of primary T cells.Marschner S., Hunig T., Cambier J.C., Finkel T.H.View abstractCategoriesFunction, InteractionSourceMGI: 88335PubMedEurope PMCImmunol Lett 82:131-139 (2002)Mapped to4