MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease.
The present results suggested that ROCK1 inhibitor could attenuate mechanical stretchinduced lung endothelial injury and the phosphorylation of MYPT1 in vivo and in vitro. Collectively the present findings indicated that upregulation of SPHK1 may contribute to VALI in a twohit model.
The findings define the PI3K/NUAK1/MYPT1/MLCP axis as a critical pathway to regulate actomyosin contractility in endothelial cells supporting vascular patterning and expansion through the control of cell rearrangement.
Phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) and MYPT1 isoform expression differentially regulates tone via NO/cGMP signaling in cerebral arteries compared to femoral arteries.
revealed the presence of two MYPT1 isoforms full length and variant 2 in human intestinal (Caco-2) epithelial cells and isolated intestinal epithelial cells from mice
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.