Q3TRK9 · Q3TRK9_MOUSE

  • Protein
    Monocarboxylate transporter 1
  • Gene
    Slc16a1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

  • (R)-3-hydroxybutanoate(out) + H+(out) = (R)-3-hydroxybutanoate(in) + H+(in)
    This reaction proceeds in the forward
    and the backward
    directions.
  • (S)-lactate(in) + H+(in) = (S)-lactate(out) + H+(out)
    This reaction proceeds in the forward
    and the backward
    directions.
  • 3-methyl-2-oxobutanoate(out) + H+(out) = 3-methyl-2-oxobutanoate(in) + H+(in)
  • 4-methyl-2-oxopentanoate(out) + H+(out) = 4-methyl-2-oxopentanoate(in) + H+(in)
  • acetoacetate(out) + H+(out) = acetoacetate(in) + H+(in)
    This reaction proceeds in the forward
    and the backward
    directions.

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentbasolateral plasma membrane
Cellular Componentlateral plasma membrane
Molecular Functionmonocarboxylic acid transmembrane transporter activity

Names & Taxonomy

Protein names

  • Recommended name
    Monocarboxylate transporter 1
  • Alternative names
    • Solute carrier family 16 member 1

Gene names

    • Name
      Slc16a1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3TRK9

Organism-specific databases

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Basolateral cell membrane
; Multi-pass membrane protein
Lateral cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane17-36Helical
Transmembrane88-105Helical
Transmembrane111-132Helical
Transmembrane144-164Helical
Transmembrane176-195Helical
Transmembrane256-280Helical
Transmembrane324-340Helical
Transmembrane346-368Helical
Transmembrane380-402Helical
Transmembrane414-436Helical

Keywords

PTM/Processing

PTM databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain19-445Major facilitator superfamily (MFS) profile
Compositional bias447-472Basic and acidic residues
Region447-493Disordered
Compositional bias473-493Polar residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    493
  • Mass (Da)
    53,301
  • Last updated
    2005-10-11 v1
  • Checksum
    856D4B7DEB3EAD7D
MPPAIGGPVGYTPPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLFGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQQHSSGDPTEEESPV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias447-472Basic and acidic residues
Compositional bias473-493Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK162682
EMBL· GenBank· DDBJ
BAE37020.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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