Q3TN26 · Q3TN26_MOUSE
- Proteinlong-chain-fatty-acid--CoA ligase
- GeneSlc27a1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids629 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoAThis reaction proceeds in the forward direction.
- a fatty acid(in) = a fatty acid(out)
- a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphateThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ligase activity | |
Molecular Function | nucleotide binding | |
Biological Process | lipid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namelong-chain-fatty-acid--CoA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ3TN26
Organism-specific databases
PTM/Processing
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 65-418 | AMP-dependent synthetase/ligase | ||||
Sequence: FQAVARRQPERLALVDASSGICWTFAQLDTYSNAVANLFRQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPESILPDTQLLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGVGQCVIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVEQRHRVRLAVGNGLRPAIWEEFTQRFGVPQIGEFYGATECNCSIANMDGKVGSCGFNSRILTHVYPIRLVKVNEDTMEPLRDS | ||||||
Domain | 506-581 | AMP-binding enzyme C-terminal | ||||
Sequence: EVEAVLSRLLGQTDVAVYGVAVPGVEGKAGMAAIADPHSQLDPNSMYQELQKVLASYARPIFLRLLPQVDTTGTFK |
Sequence similarities
Belongs to the ATP-dependent AMP-binding enzyme family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length629
- Mass (Da)69,410
- Last updated2005-10-11 v1
- Checksum886F316F9BE58396