PI(4,5)P<sub>2</sub>-dependent regulation of endothelial tip cell specification contributes to angiogenesis.Davies E.M., Gurung R., Le K.Q., Roan K.T.T., Harvey R.P., Mitchell G.M., Schwarz Q., Mitchell C.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCSci Adv 9:eadd6911-eadd6911 (2023)Mapped to20
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock.Le T.N.U., Nguyen T.Q., Kalailingam P., Nguyen Y.T.K., Sukumar V.K., Tan C.K.H., Tukijan F., Couty L., Hasan Z.[...], Nguyen L.N.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCCell Rep 40:111208-111208 (2022)Mapped to84
Endothelial Cyp26b1 restrains murine heart valve growth during development.Ahuja N., Hiltabidle M.S., Rajasekhar H., Voss S., Lu S.Z., Barlow H.R., Cowdin M.A., Daniel E., Vaddaraju V.[...], Maynard C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev Biol 486:81-95 (2022)Mapped to99+
VE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling.Harris N.R., Nielsen N.R., Pawlak J.B., Aghajanian A., Rangarajan K., Serafin D.S., Farber G., Dy D.M., Nelson-Maney N.P.[...], Caron K.M.View abstractAnnotationVE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 12562PubMedEurope PMCCirc Res 130:5-23 (2022)Mapped to2
eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin.Ninchoji T., Love D.T., Smith R.O., Hedlund M., Vestweber D., Sessa W.C., Claesson-Welsh L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCElife 10:e64944-e64944 (2021)Mapped to13
Catenin alpha 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/beta-catenin signaling.Zhu X., Yang M., Zhao P., Li S., Zhang L., Huang L., Huang Y., Fei P., Yang Y.[...], Yang Z.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCJ Clin Invest 131:139869-139869 (2021)Mapped to53
Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin.Smith R.O., Ninchoji T., Gordon E., Andre H., Dejana E., Vestweber D., Kvanta A., Claesson-Welsh L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCElife 9:e54056-e54056 (2020)Mapped to9
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.Tian X., He L., Liu K., Pu W., Zhao H., Li Y., Liu X., Tang M., Sun R.[...], Zhou B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCEMBO J 39:e102675-e102675 (2020)Mapped to29
VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance.Yang Y., Cha B., Motawe Z.Y., Srinivasan R.S., Scallan J.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCCell Rep 28:2397-2412.e4 (2019)Mapped to49
Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function.Patel M.M., Behar A.R., Silasi R., Regmi G., Sansam C.L., Keshari R.S., Lupu F., Lupu C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCJ Am Heart Assoc 7:e010690-e010690 (2018)Cited in1Mapped to99+
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.Nonomura K., Lukacs V., Sweet D.T., Goddard L.M., Kanie A., Whitwam T., Ranade S.S., Fujimori T., Kahn M.L., Patapoutian A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCProc Natl Acad Sci U S A 115:12817-12822 (2018)Mapped to41
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.Kim H.T., Yin W., Jin Y.J., Panza P., Gunawan F., Grohmann B., Buettner C., Sokol A.M., Preussner J.[...], Stainier D.Y.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCNat Commun 9:4600-4600 (2018)Mapped to99+
CCBE1 is required for coronary vessel development and proper coronary artery stem formation in the mouse heart.Bonet F., Pereira P.N.G., Bover O., Marques S., Inacio J.M., Belo J.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev Dyn 247:1135-1145 (2018)Mapped to25
Myocardial beta-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.Wang Y., Lu P., Wu B., Riascos-Bernal D.F., Sibinga N.E.S., Valenta T., Basler K., Zhou B.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCJ Mol Cell Cardiol 123:150-158 (2018)Mapped to99+
Developmental SMAD6 loss leads to blood vessel hemorrhage and disrupted endothelial cell junctions.Wylie L.A., Mouillesseaux K.P., Chong D.C., Bautch V.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev Biol 442:199-209 (2018)Mapped to31
Pax6 regulation of <i>Sox9</i> in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development.Cohen-Tayar Y., Cohen H., Mitiagin Y., Abravanel Z., Levy C., Idelson M., Reubinoff B., Itzkovitz S., Raviv S.[...], Ashery-Padan R.View abstractCategoriesFunction, Expression, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDevelopment 145:dev163691-dev163691 (2018)Mapped to45
Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain.Dave J.M., Mirabella T., Weatherbee S.D., Greif D.M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev Cell 44:665-678.e6 (2018)Mapped to59
Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.Zhang Y., Daubel N., Stritt S., Makinen T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDevelopment 145:dev156745-dev156745 (2018)Mapped to29
Alternative progenitor cells compensate to rebuild the coronary vasculature in Elabela- and Apj-deficient hearts.Sharma B., Ho L., Ford G.H., Chen H.I., Goldstone A.B., Woo Y.J., Quertermous T., Reversade B., Red-Horse K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev. Cell 42:655-666 (2017)Cited in3Mapped to54
Loss of Apela peptide in mice causes low penetrance embryonic lethality and defects in early mesodermal derivatives.Freyer L., Hsu C.W., Nowotschin S., Pauli A., Ishida J., Kuba K., Fukamizu A., Schier A.F., Hoodless P.A.[...], Hadjantonakis A.K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCCell Rep. 20:2116-2130 (2017)Cited in3Mapped to68
Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura.Tischfield M.A., Robson C.D., Gilette N.M., Chim S.M., Sofela F.A., DeLisle M.M., Gelber A., Barry B.J., MacKinnon S.[...], Engle E.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDev Cell 42:445-461.e5 (2017)Mapped to75
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.Doring Y., Noels H., van der Vorst E.P.C., Neideck C., Egea V., Drechsler M., Mandl M., Pawig L., Jansen Y.[...], Weber C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCCirculation 136:388-403 (2017)Mapped to12
Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.Morooka N., Futaki S., Sato-Nishiuchi R., Nishino M., Totani Y., Shimono C., Nakano I., Nakajima H., Mochizuki N., Sekiguchi K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCCirc. Res. 120:1276-1288 (2017)Cited in21Mapped to31
Blood flow controls bone vascular function and osteogenesis.Ramasamy S.K., Kusumbe A.P., Schiller M., Zeuschner D., Bixel M.G., Milia C., Gamrekelashvili J., Limbourg A., Medvinsky A.[...], Adams R.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCNat Commun 7:13601-13601 (2016)Mapped to71
Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.Wang Y., Baeyens N., Corti F., Tanaka K., Fang J.S., Zhang J., Jin Y., Coon B., Hirschi K.K.[...], Simons M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 105057PubMedEurope PMCDevelopment 143:4441-4451 (2016)Mapped to43