Impact of heterogeneous nuclear ribonucleoprotein A/B subtype overexpression on the expression of cancer stem cell markers CD133 and CD44 and cellular proliferation capacity.
Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells.
HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis.
these studies suggest that CUG(exp) RNA triggers abnormal expression of multiple nuclear RNA binding proteins including CELF1 and HNRNPA1 that antagonize MBNL activity to promote fetal splicing patterns
hnRNPA1 is a critical regulator of vascular smooth muscle cell function and behavior in the context of neointima hyperplasia via miR-124/IQGAP1 regulatory axis.
Resveratrol causes a shift from the mesenchymal-specific forms of these factors to the respective epithelial forms and increases the expression of the RNA-binding proteins KHSRP and hnRNPA1.
this study identified hnRNPA1 an RNA-binding protein and auxiliary splicing factor as a substrate of TRAF6; TRAF6 ubiquitination of hnRNPA1 regulated alternative splicing of Arhgap1 which resulted in activation of the GTP-binding Rho family protein Cdc42 and accounted for hematopoietic defects in TRAF6-expressing hematopoietic stem/ progenitor cells
hnRNP A1 improves intestinal injury in anti-CD3 antibody-induced enteritis mice through the upregulation of TFF2 which regulates apoptosis and enhances epithelial restoration
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.